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Phactr1
Gene Detail
Symbol

Name
ID
Phactr1
phosphatase and actin regulator 1
MGI:2659021
Synonyms
9630030F18Rik, Rpel1
Feature Type
protein coding gene
Genetic Map
Chromosome 13
21.05 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:42680623-43138526 bp, + strand
From VEGA annotation of GRCm38

  457904 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:33597  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: phosphatase and actin regulator
Gene Tree: Phactr1

Human
homologs
Human Homolog PHACTR1, phosphatase and actin regulator 1
NCBI Gene ID 221692
neXtProt AC  NX_Q9C0D0
Human Synonyms  dJ257A7.2, RPEL, RPEL1
Human Chr (Location)  6p24.1; chr6:12716656-13290244 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Phactr1 interacts with 342 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process actin cytoskeleton reorganization, actomyosin structure organization, ...
Component cell junction, cytoplasm, ...
Function actin binding, protein phosphatase 1 binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (14)    Tissues (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 14
cDNA source data(59)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(61) cDNA(61)
Microarray probesets(6)
Other database
links
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023876 VEGA Gene Model | MGI Sequence Detail 457904 C57BL/6J ±  kb
transcript OTTMUST00000065150 VEGA | MGI Sequence Detail 5307 Not Applicable 
polypeptide OTTMUSP00000032430 VEGA | MGI Sequence Detail 642 Not Applicable 

For the selected sequences
All sequences(104) RefSeq(20) UniProt(7)
Polymorphisms
SNPs within 2kb(3297 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004018 RPEL repeat
Protein Ontology PR:000012626 phosphatase and actin regulator 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:196227 Wiezlak M, et al., G-actin regulates the shuttling and PP1 binding of the RPEL protein Phactr1 to control actomyosin assembly. J Cell Sci. 2012 Dec 1;125(Pt 23):5860-72
All references(35)
Other
accession IDs
MGI:1925996

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory