Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PGLYRP1
  • Mouse genes Pglyrp1
  • Rat genes Pglyrp1
  • Zfish genes pglyrp5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pglyrp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030544	Hsp70 protein binding	PGLYRP1	IDA		Human	PMID:14585845
Molecular Function	GO:0060090	molecular adaptor activity	PGLYRP1	IDA		Human	PMID:26654597
Molecular Function	GO:0140677	molecular function activator activity	PGLYRP1	IDA		Human	PMID:14585845
Molecular Function	GO:0140677	molecular function activator activity	PGLYRP1	IDA		Human	PMID:26654597
Molecular Function	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity	pglyrp5	IDA		Zfish	PMID:17892854
Molecular Function	GO:0042834	peptidoglycan binding	PGLYRP1	IDA		Human	PMID:11461926
Molecular Function	GO:0042834	peptidoglycan binding	PGLYRP1	IDA		Human	PMID:16354652
Molecular Function	GO:0042834	peptidoglycan binding	PGLYRP1	IDA		Human	PMID:17502600
Molecular Function	GO:0016019	peptidoglycan immune receptor activity	PGLYRP1	IDA		Human	PMID:11461926
Molecular Function	GO:0048018	receptor ligand activity	PGLYRP1	IDA		Human	PMID:25595774
Cellular Component	GO:0070062	extracellular exosome	PGLYRP1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	PGLYRP1	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	PGLYRP1	IDA		Human	PMID:14585845
Cellular Component	GO:0005615	extracellular space	PGLYRP1	IDA		Human	PMID:25595774
Cellular Component	GO:0005615	extracellular space	PGLYRP1	IDA		Human	PMID:26654597
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	PGLYRP1	IDA		Human	PMID:16354652
Biological Process	GO:0051701	biological process involved in interaction with host	Pglyrp1	IMP	MGI:MGI:2670590	Mouse	PMID:20709292
Biological Process	GO:0042742	defense response to bacterium	pglyrp5	IMP	ZFIN:ZDB-MRPHLNO-071227-3	Zfish	PMID:17892854
Biological Process	GO:0042742	defense response to bacterium	pglyrp5	IDA		Zfish	PMID:17892854
Biological Process	GO:0050830	defense response to Gram-positive bacterium	PGLYRP1	IDA		Human	PMID:11461926
Biological Process	GO:0050830	defense response to Gram-positive bacterium	PGLYRP1	IDA		Human	PMID:16354652
Biological Process	GO:0016045	detection of bacterium	PGLYRP1	IDA		Human	PMID:11461926
Biological Process	GO:0031640	killing of cells of another organism	PGLYRP1	IDA		Human	PMID:16354652
Biological Process	GO:0050728	negative regulation of inflammatory response	Pglyrp1	IMP	MGI:MGI:2670590	Mouse	PMID:19218085
Biological Process	GO:0032827	negative regulation of natural killer cell differentiation involved in immune response	Pglyrp1	IMP	MGI:MGI:2670590	Mouse	PMID:20709292
Biological Process	GO:0032689	negative regulation of type II interferon production	Pglyrp1	IMP	MGI:MGI:2670590	Mouse	PMID:20709292
Biological Process	GO:0045187	regulation of circadian sleep/wake cycle, sleep	Pglyrp1	IEP		Rat	PMID:11145837|RGD:724610
Biological Process	GO:0009617	response to bacterium	Pglyrp1	IEP		Mouse	PMID:23012479

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern