Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PGAM5
  • Mouse genes Pgam5
  • Rat genes Pgam5
  • Zfish genes pgam5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pgam5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	PGAM5	IMP		Human	PMID:22265414
Molecular Function	GO:0016791	phosphatase activity	PGAM5	IMP		Human	PMID:22265414
Molecular Function	GO:0005515	protein binding	PGAM5	IPI	UniProtKB:Q99683	Human	PMID:19590015
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	PGAM5	IDA		Human	PMID:19590015
Molecular Function	GO:0044877	protein-containing complex binding	PGAM5	IDA		Human	PMID:22265414
Cellular Component	GO:0005739	mitochondrion	PGAM5	IDA		Human	GO_REF:0000052
Biological Process	GO:0070266	necroptotic process	PGAM5	IMP		Human	PMID:22265414
Biological Process	GO:0070266	necroptotic process	Pgam5	IMP		Mouse	MGI:MGI:5516181|PMID:22265414
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	Pgam5	IMP		Mouse	MGI:MGI:6150557|PMID:27077115

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern