Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PDLIM2
  • Mouse genes Pdlim2
  • Rat genes Pdlim2
  • Zfish genes pdlim2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pdlim2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051393	alpha-actinin binding	Pdlim2	IPI	RGD:61816	Rat	PMID:15505042|RGD:1359754
Molecular Function	GO:0051393	alpha-actinin binding	Pdlim2	IPI	RGD:70907	Rat	PMID:15505042|RGD:1359754
Molecular Function	GO:0031005	filamin binding	Pdlim2	IPI	RGD:1560614	Rat	PMID:15505042|RGD:1359754
Molecular Function	GO:0051371	muscle alpha-actinin binding	Pdlim2	IPI	RGD:1308097	Rat	PMID:15505042|RGD:1359754
Molecular Function	GO:0032036	myosin heavy chain binding	Pdlim2	IPI	RGD:3140	Rat	PMID:15505042|RGD:1359754
Molecular Function	GO:0005515	protein binding	PDLIM2	IPI	UniProtKB:Q96AP0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	PDLIM2	IPI	UniProtKB:Q8IW36-1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Pdlim2	IPI	UniProtKB:Q64669	Mouse	PMID:29934320
Molecular Function	GO:0005515	protein binding	Pdlim2	IPI	RGD:1560646	Rat	PMID:15505042|RGD:1359754
Molecular Function	GO:0005515	protein binding	Pdlim2	IPI	RGD:61816	Rat	PMID:15505042|RGD:1359754
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Pdlim2	IPI	UniProtKB:Q9ERV1	Mouse	MGI:MGI:6296023|PMID:28378844
Cellular Component	GO:0030864	cortical actin cytoskeleton	Pdlim2	IDA		Rat	PMID:15505042|RGD:1359754
Cellular Component	GO:0001725	stress fiber	Pdlim2	IDA		Rat	PMID:15505042|RGD:1359754
Biological Process	GO:0030163	protein catabolic process	Pdlim2	IMP	MGI:MGI:3623895	Mouse	PMID:29934320

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern