Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PCSK7
  • Mouse genes Pcsk7
  • Rat genes Pcsk7
  • Zfish genes pcsk7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pcsk7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008233	peptidase activity	PCSK7	IDA		Human	PMID:15606899
Molecular Function	GO:0005515	protein binding	PCSK7	IPI	UniProtKB:P14136	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PCSK7	IPI	UniProtKB:P16284	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PCSK7	IPI	UniProtKB:P17612	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PCSK7	IPI	UniProtKB:P19404	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PCSK7	IPI	UniProtKB:P29474	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PCSK7	IPI	UniProtKB:P37173	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PCSK7	IPI	UniProtKB:P50454	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PCSK7	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PCSK7	IPI	UniProtKB:Q92876	Human	PMID:32814053
Cellular Component	GO:0000139	Golgi membrane	PCSK7	IDA		Human	PMID:9341152
Biological Process	GO:0007420	brain development	pcsk7	IMP	ZFIN:ZDB-MRPHLNO-140403-3	Zfish	PMID:24178295
Biological Process	GO:0043009	chordate embryonic development	pcsk7	IMP	ZFIN:ZDB-MRPHLNO-140403-4	Zfish	PMID:24178295
Biological Process	GO:0043009	chordate embryonic development	pcsk7	IMP	ZFIN:ZDB-MRPHLNO-140403-3	Zfish	PMID:24178295
Biological Process	GO:0001654	eye development	pcsk7	IMP	ZFIN:ZDB-MRPHLNO-140403-3	Zfish	PMID:24178295
Biological Process	GO:0048840	otolith development	pcsk7	IMP	ZFIN:ZDB-MRPHLNO-140403-3	Zfish	PMID:24178295
Biological Process	GO:0048840	otolith development	pcsk7	IMP	ZFIN:ZDB-MRPHLNO-140403-4	Zfish	PMID:24178295
Biological Process	GO:0016485	protein processing	PCSK7	IDA		Human	PMID:15606899

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern