Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PCBP2
  • Mouse genes Pcbp2
  • Rat genes Pcbp2
  • Zfish genes pcbp2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pcbp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990829	C-rich single-stranded DNA binding	Pcbp2	IDA		Mouse	PMID:8208614
Molecular Function	GO:0003677	DNA binding	Pcbp2	IDA		Mouse	PMID:8367306
Molecular Function	GO:0019899	enzyme binding	PCBP2	IPI	UniProtKB:Q9BYX4	Human	PMID:19881509
Molecular Function	GO:0003730	mRNA 3'-UTR binding	pcbp2	IDA		Zfish	PMID:31227602
Molecular Function	GO:0005515	protein binding	PCBP2	IPI	UniProtKB:Q15365	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	PCBP2	IPI	UniProtKB:P84103	Human	PMID:17183366
Molecular Function	GO:0005515	protein binding	PCBP2	IPI	UniProtKB:Q7Z434	Human	PMID:19881509
Molecular Function	GO:0005515	protein binding	PCBP2	IPI	UniProtKB:Q8IWS0	Human	PMID:22720776
Molecular Function	GO:0005515	protein binding	PCBP2	IPI	UniProtKB:P09012	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PCBP2	IDA		Human	PMID:35322803
Molecular Function	GO:0005515	protein binding	PCBP2	IPI	UniProtKB:Q8N884	Human	PMID:35322803
Molecular Function	GO:0005515	protein binding	Pcbp2	IPI	PR:Q8BL97	Mouse	PMID:8871564
Molecular Function	GO:0005515	protein binding	Pcbp2	IPI	PR:Q8BTM8	Mouse	PMID:8871564
Molecular Function	GO:0005515	protein binding	Pcbp2	IPI	PR:Q9CPN8	Mouse	PMID:8871564
Molecular Function	GO:0005515	protein binding	Pcbp2	IPI	PR:Q8R081	Mouse	PMID:8871564
Molecular Function	GO:0005515	protein binding	Pcbp2	IPI	PR:P62960	Mouse	PMID:8871564
Molecular Function	GO:0003723	RNA binding	PCBP2	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	PCBP2	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	PCBP2	IDA		Human	PMID:7607214
Molecular Function	GO:0003697	single-stranded DNA binding	Pcbp2	IDA		Mouse	PMID:24026233
Molecular Function	GO:0031625	ubiquitin protein ligase binding	PCBP2	IPI	UniProtKB:Q8IUD6	Human	PMID:19881509
Molecular Function	GO:0031625	ubiquitin protein ligase binding	PCBP2	IPI	UniProtKB:Q96J02	Human	PMID:19881509
Cellular Component	GO:0005737	cytoplasm	PCBP2	IDA		Human	PMID:19029303
Cellular Component	GO:0005829	cytosol	PCBP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	PCBP2	HDA		Human	PMID:23533145
Cellular Component	GO:0005925	focal adhesion	PCBP2	HDA		Human	PMID:21423176
Cellular Component	GO:0016020	membrane	PCBP2	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	PCBP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PCBP2	IDA		Human	PMID:22720776
Cellular Component	GO:0005634	nucleus	Pcbp2	IDA		Mouse	PMID:8871564
Cellular Component	GO:0014069	postsynaptic density	Pcbp2	EXP		Rat	PMID:16507876|RGD:13702274
Cellular Component	GO:0014069	postsynaptic density	Pcbp2	IDA		Rat	PMID:16507876|RGD:13702274
Biological Process	GO:0075522	IRES-dependent viral translational initiation	PCBP2	IDA		Human	PMID:12414943
Biological Process	GO:0050687	negative regulation of defense response to virus	PCBP2	IMP		Human	PMID:19881509
Biological Process	GO:0045824	negative regulation of innate immune response	PCBP2	IDA		Human	PMID:35322803
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pcbp2	IDA		Mouse	PMID:24026233
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	PCBP2	IMP		Human	PMID:19881509
Biological Process	GO:0039694	viral RNA genome replication	PCBP2	IDA		Human	PMID:12414943

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern