Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PAXX
  • Mouse genes Paxx
  • Rat genes Paxx
  • Zfish genes paxx
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Paxx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070182	DNA polymerase binding	PAXX	IPI	UniProtKB:Q9UGP5	Human	PMID:30250067
Molecular Function	GO:0060090	molecular adaptor activity	PAXX	IDA		Human	PMID:25670504
Molecular Function	GO:0005515	protein binding	PAXX	IPI	UniProtKB:P12956	Human	PMID:25574025
Molecular Function	GO:0005515	protein binding	PAXX	IPI	UniProtKB:P13010	Human	PMID:25574025
Molecular Function	GO:0005515	protein binding	PAXX	IPI	UniProtKB:P13010	Human	PMID:31548606
Molecular Function	GO:0005515	protein binding	PAXX	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Molecular Function	GO:0042803	protein homodimerization activity	PAXX	IDA		Human	PMID:25574025
Cellular Component	GO:0070419	nonhomologous end joining complex	PAXX	IDA		Human	PMID:25670504
Cellular Component	GO:0070419	nonhomologous end joining complex	PAXX	IDA		Human	PMID:25941166
Cellular Component	GO:0005654	nucleoplasm	PAXX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PAXX	IDA		Human	PMID:25574025
Cellular Component	GO:0035861	site of double-strand break	PAXX	IDA		Human	PMID:25670504
Biological Process	GO:0006974	DNA damage response	PAXX	IDA		Human	PMID:25574025
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	PAXX	IMP		Human	PMID:25574025
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	PAXX	IMP		Human	PMID:25670504
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	PAXX	IMP		Human	PMID:25941166
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	PAXX	IDA		Human	PMID:30250067
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	Paxx	IMP		Mouse	MGI:MGI:5807276|PMID:27798842
Biological Process	GO:0006303	double-strand break repair via nonhomologous end joining	Paxx	IMP		Mouse	MGI:MGI:5822993|PMID:28051062

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern