Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PALM
  • Mouse genes Palm
  • Rat genes Palm
  • Zfish genes palm1a,palm1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Palm

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031750	D3 dopamine receptor binding	Palm	IPI	PR:P30728	Mouse	PMID:16386234
Molecular Function	GO:0005515	protein binding	PALM	IPI	UniProtKB:P35462	Human	PMID:16386234
Molecular Function	GO:0005515	protein binding	PALM	IPI	UniProtKB:G5E9A7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PALM	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Cellular Component	GO:0016327	apicolateral plasma membrane	Palm	IDA		Rat	PMID:16847661|RGD:8554086
Cellular Component	GO:0030424	axon	Palm	IDA		Rat	PMID:16847661|RGD:8554086
Cellular Component	GO:0016323	basolateral plasma membrane	Palm	IDA		Rat	PMID:16847661|RGD:8554086
Cellular Component	GO:0005737	cytoplasm	Palm	IDA		Mouse	PMID:9813098
Cellular Component	GO:0032590	dendrite membrane	Palm	IDA		Rat	PMID:16847661|RGD:8554086
Cellular Component	GO:0032591	dendritic spine membrane	Palm	IDA		Rat	PMID:16847661|RGD:8554086
Cellular Component	GO:0030175	filopodium	Palm	IDA		Mouse	MGI:MGI:5009384|PMID:18287537
Cellular Component	GO:0031527	filopodium membrane	PALM	IDA		Human	PMID:14978216
Cellular Component	GO:0044309	neuron spine	Palm	IDA		Mouse	MGI:MGI:5009384|PMID:18287537
Cellular Component	GO:0005654	nucleoplasm	PALM	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	PALM	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	PALM	IDA		Human	PMID:16386234
Cellular Component	GO:0005886	plasma membrane	Palm	IDA		Mouse	MGI:MGI:5009384|PMID:18287537
Cellular Component	GO:0005886	plasma membrane	Palm	IDA		Mouse	PMID:16386234
Cellular Component	GO:0005886	plasma membrane	Palm	IDA		Mouse	PMID:9813098
Cellular Component	GO:0005886	plasma membrane	Palm	IDA		Rat	PMID:16847661|RGD:8554086
Cellular Component	GO:0014069	postsynaptic density	Palm	IDA		Mouse	PMID:17114649
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	Palm	IDA		Mouse	PMID:16386234
Biological Process	GO:0071257	cellular response to electrical stimulus	Palm	IDA		Mouse	MGI:MGI:5009384|PMID:18287537
Biological Process	GO:0007010	cytoskeleton organization	Palm	IDA		Mouse	PMID:9813098
Biological Process	GO:0007194	negative regulation of adenylate cyclase activity	Palm	IDA		Mouse	PMID:16386234
Biological Process	GO:0060160	negative regulation of dopamine receptor signaling pathway	PALM	IDA		Human	PMID:16386234
Biological Process	GO:0060999	positive regulation of dendritic spine development	Palm	IDA		Mouse	MGI:MGI:5009384|PMID:18287537
Biological Process	GO:0051491	positive regulation of filopodium assembly	PALM	IDA		Human	PMID:14978216
Biological Process	GO:0051491	positive regulation of filopodium assembly	Palm	IDA		Mouse	MGI:MGI:5009384|PMID:18287537
Biological Process	GO:0008104	protein localization	Palm	IDA		Mouse	PMID:16386234
Biological Process	GO:0072659	protein localization to plasma membrane	Palm	IDA		Mouse	MGI:MGI:5009384|PMID:18287537
Biological Process	GO:0008360	regulation of cell shape	Palm	IDA		Mouse	PMID:9813098
Biological Process	GO:0060074	synapse maturation	Palm	IDA		Mouse	MGI:MGI:5009384|PMID:18287537

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern