Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PAG1
  • Mouse genes Pag1
  • Rat genes Pag1
  • Zfish genes pag1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pag1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PAG1	IPI	UniProtKB:P06241	Human	PMID:10790433
Molecular Function	GO:0005515	protein binding	PAG1	IPI	UniProtKB:P41240	Human	PMID:10790433
Molecular Function	GO:0005515	protein binding	PAG1	IPI	UniProtKB:O14745,UniProtKB:P15311,UniProtKB:P41240	Human	PMID:17911601
Molecular Function	GO:0005515	protein binding	PAG1	IPI	UniProtKB:P06241	Human	PMID:18056706
Molecular Function	GO:0005515	protein binding	PAG1	IPI	UniProtKB:P07948	Human	PMID:18070987
Molecular Function	GO:0005515	protein binding	PAG1	IPI	UniProtKB:P41240	Human	PMID:18070987
Molecular Function	GO:0005515	protein binding	PAG1	IPI	UniProtKB:P06241	Human	PMID:23866081
Molecular Function	GO:0005515	protein binding	PAG1	IPI	UniProtKB:P07948	Human	PMID:23866081
Molecular Function	GO:0005515	protein binding	PAG1	IPI	UniProtKB:P63244	Human	PMID:23866081
Molecular Function	GO:0005515	protein binding	PAG1	IPI	UniProtKB:P41240	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PAG1	IPI	UniProtKB:P41240	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Pag1	IPI	UniProtKB:P41241	Mouse	MGI:MGI:5825414|PMID:26512138
Molecular Function	GO:0005515	protein binding	Pag1	IPI	UniProtKB:P41241	Mouse	MGI:MGI:3687921|PMID:12612075
Molecular Function	GO:0042169	SH2 domain binding	PAG1	IDA		Human	PMID:10790433
Cellular Component	GO:0045121	membrane raft	PAG1	IDA		Human	PMID:10790433
Cellular Component	GO:0005886	plasma membrane	PAG1	IDA		Human	PMID:10790433
Biological Process	GO:0035556	intracellular signal transduction	PAG1	IDA		Human	PMID:10790433
Biological Process	GO:0050868	negative regulation of T cell activation	Pag1	IDA		Mouse	MGI:MGI:3687921|PMID:12612075
Biological Process	GO:0050863	regulation of T cell activation	PAG1	IDA		Human	PMID:10790433

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern