Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PADI4
  • Mouse genes Padi4
  • Rat genes Padi4
  • Zfish genes padi2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Padi4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	PADI4	IDA		Human	PMID:16567635
Molecular Function	GO:0140794	histone arginine deiminase activity	PADI4	IDA		Human	PMID:16567635
Molecular Function	GO:0140794	histone arginine deiminase activity	padi2	IMP	ZFIN:ZDB-GENO-210506-12	Zfish	PMID:32328635
Molecular Function	GO:0140797	histone H3R17 arginine deiminase activity	PADI4	IDA		Human	PMID:15339660
Molecular Function	GO:0140797	histone H3R17 arginine deiminase activity	PADI4	IDA		Human	PMID:15345777
Molecular Function	GO:0140795	histone H3R2 arginine deiminase activity	PADI4	IDA		Human	PMID:15339660
Molecular Function	GO:0140795	histone H3R2 arginine deiminase activity	PADI4	IDA		Human	PMID:15345777
Molecular Function	GO:0140798	histone H3R26 arginine deiminase activity	PADI4	IDA		Human	PMID:15339660
Molecular Function	GO:0140798	histone H3R26 arginine deiminase activity	PADI4	IDA		Human	PMID:15345777
Molecular Function	GO:0140796	histone H3R8 arginine deiminase activity	PADI4	IDA		Human	PMID:15339660
Molecular Function	GO:0140796	histone H3R8 arginine deiminase activity	PADI4	IDA		Human	PMID:15345777
Molecular Function	GO:0042802	identical protein binding	PADI4	IPI	UniProtKB:Q9UM07	Human	PMID:15247907
Molecular Function	GO:0005515	protein binding	PADI4	IPI	UniProtKB:P09525	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PADI4	IPI	UniProtKB:P09525	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PADI4	IPI	UniProtKB:P78424	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PADI4	IPI	UniProtKB:Q96RU7	Human	PMID:32296183
Molecular Function	GO:0004668	protein-arginine deiminase activity	PADI4	IMP		Human	PMID:15247907
Molecular Function	GO:0004668	protein-arginine deiminase activity	PADI4	IDA		Human	PMID:21584310
Molecular Function	GO:0004668	protein-arginine deiminase activity	Padi4	IDA		Mouse	MGI:MGI:5545819|PMID:24463520
Molecular Function	GO:0004668	protein-arginine deiminase activity	Padi4	IDA		Rat	PMID:12392711|RGD:8554540
Molecular Function	GO:0004668	protein-arginine deiminase activity	Padi4	IDA		Rat	PMID:9738944|RGD:69924
Cellular Component	GO:0005634	nucleus	PADI4	IDA		Human	PMID:15339660
Cellular Component	GO:0032991	protein-containing complex	PADI4	IMP		Human	PMID:15247907
Biological Process	GO:0006325	chromatin organization	Padi4	IMP		Mouse	MGI:MGI:5545819|PMID:24463520
Biological Process	GO:0006338	chromatin remodeling	Padi4	IMP		Mouse	MGI:MGI:5545819|PMID:24463520
Biological Process	GO:0006334	nucleosome assembly	Padi4	IMP		Mouse	MGI:MGI:5545819|PMID:24463520
Biological Process	GO:0043687	post-translational protein modification	PADI4	IMP		Human	PMID:15247907
Biological Process	GO:0043687	post-translational protein modification	PADI4	IDA		Human	PMID:15339660
Biological Process	GO:0043687	post-translational protein modification	PADI4	IDA		Human	PMID:21584310
Biological Process	GO:0019827	stem cell population maintenance	Padi4	IMP		Mouse	MGI:MGI:5545819|PMID:24463520
Biological Process	GO:0001944	vasculature development	padi2	IMP	ZFIN:ZDB-MRPHLNO-170818-2	Zfish	PMID:28617813
Biological Process	GO:0001944	vasculature development	padi2	IMP	ZFIN:ZDB-MRPHLNO-170818-1	Zfish	PMID:28617813

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern