Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PACSIN3
  • Mouse genes Pacsin3
  • Rat genes Pacsin3
  • Zfish genes pacsin3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pacsin3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019855	calcium channel inhibitor activity	Pacsin3	IMP		Mouse	MGI:MGI:5486547|PMID:18174177
Molecular Function	GO:0008092	cytoskeletal protein binding	Pacsin3	IDA		Mouse	PMID:11082044
Molecular Function	GO:0042802	identical protein binding	PACSIN3	IPI	UniProtKB:Q9UKS6	Human	PMID:32296183
Molecular Function	GO:0008289	lipid binding	PACSIN3	IDA		Human	PMID:23236520
Molecular Function	GO:0008289	lipid binding	Pacsin3	IDA		Mouse	MGI:MGI:5487500|PMID:22573331
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:Q13443	Human	PMID:10531379
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:Q13444	Human	PMID:10531379
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:Q07889	Human	PMID:14679214
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:Q07890	Human	PMID:14679214
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:P48023	Human	PMID:16318909
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:Q13444	Human	PMID:16374509
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:O14672	Human	PMID:25036101
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:O43597	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:Q9BY11	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:Q9UHV8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:Q9BY11	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:Q9BY11	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:O00401	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:O14787-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:P59991	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:Q96GM5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:Q9BY11	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PACSIN3	IPI	UniProtKB:Q9UNF0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Pacsin3	IPI	UniProtKB:Q9EPK8	Mouse	MGI:MGI:5486547|PMID:18174177
Molecular Function	GO:0005515	protein binding	Pacsin3	IPI	PR:Q91YD9	Mouse	PMID:11082044
Molecular Function	GO:0005515	protein binding	Pacsin3	IPI	PR:Q61644	Mouse	PMID:11082044
Molecular Function	GO:0005515	protein binding	Pacsin3	IPI	PR:Q9WVE8	Mouse	PMID:11082044
Molecular Function	GO:0005515	protein binding	Pacsin3	IPI	PR:Q99JB8	Mouse	PMID:11082044
Cellular Component	GO:0005737	cytoplasm	Pacsin3	IDA		Mouse	PMID:11082044
Cellular Component	GO:0005829	cytosol	PACSIN3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	PACSIN3	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	PACSIN3	HDA		Human	PMID:23533145
Cellular Component	GO:0005886	plasma membrane	PACSIN3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	pacsin3	IDA		Zfish	PMID:19997509
Biological Process	GO:0051926	negative regulation of calcium ion transport	Pacsin3	IMP		Mouse	MGI:MGI:5486547|PMID:18174177
Biological Process	GO:0045806	negative regulation of endocytosis	Pacsin3	IMP		Mouse	MGI:MGI:3688821|PMID:16627472
Biological Process	GO:0045806	negative regulation of endocytosis	Pacsin3	IDA		Mouse	PMID:11082044
Biological Process	GO:0060034	notochord cell differentiation	pacsin3	IMP	ZFIN:ZDB-MRPHLNO-100223-1	Zfish	PMID:19997509
Biological Process	GO:0014028	notochord formation	pacsin3	IMP	ZFIN:ZDB-MRPHLNO-100223-1	Zfish	PMID:19997509
Biological Process	GO:0097320	plasma membrane tubulation	PACSIN3	IDA		Human	PMID:23236520
Biological Process	GO:0097320	plasma membrane tubulation	Pacsin3	IDA		Mouse	MGI:MGI:5487500|PMID:22573331
Biological Process	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	PACSIN3	IMP		Human	PMID:15280379

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern