Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OXCT1
  • Mouse genes Oxct1
  • Rat genes Oxct1
  • Zfish genes oxct1a,oxct1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Oxct1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Oxct1	IPI	RGD:1584008	Rat	PMID:20025965|RGD:2326188
Molecular Function	GO:0008260	succinyl-CoA:3-oxo-acid CoA-transferase activity	OXCT1	IMP		Human	PMID:10964512
Molecular Function	GO:0008260	succinyl-CoA:3-oxo-acid CoA-transferase activity	OXCT1	IMP		Human	PMID:8751852
Molecular Function	GO:0008260	succinyl-CoA:3-oxo-acid CoA-transferase activity	Oxct1	IDA		Mouse	PMID:12534938
Molecular Function	GO:0008260	succinyl-CoA:3-oxo-acid CoA-transferase activity	Oxct1	IDA		Rat	PMID:6950030|RGD:2326213
Cellular Component	GO:0005739	mitochondrion	OXCT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	OXCT1	IDA		Human	PMID:11756565
Cellular Component	GO:0005739	mitochondrion	Oxct1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Oxct1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Oxct1	IDA		Rat	PMID:20025965|RGD:2326188
Biological Process	GO:0060612	adipose tissue development	Oxct1	IEP		Rat	PMID:2866764|RGD:2326101
Biological Process	GO:0007420	brain development	Oxct1	IEP		Rat	PMID:5166591|RGD:2326169
Biological Process	GO:0046950	cellular ketone body metabolic process	OXCT1	IMP		Human	PMID:9671268
Biological Process	GO:0046950	cellular ketone body metabolic process	Oxct1	IDA		Mouse	PMID:12534938
Biological Process	GO:0046950	cellular ketone body metabolic process	Oxct1	IEP		Rat	PMID:3860190|RGD:2326212
Biological Process	GO:0007507	heart development	Oxct1	IEP		Rat	PMID:5166591|RGD:2326169
Biological Process	GO:0046952	ketone body catabolic process	Oxct1	IMP	MGI:MGI:4364940	Mouse	PMID:21209089
Biological Process	GO:0042182	ketone catabolic process	Oxct1	IMP	MGI:MGI:4364940	Mouse	PMID:21209089
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Oxct1	IMP		Rat	PMID:20460097|RGD:2326185
Biological Process	GO:0014823	response to activity	Oxct1	IEP		Rat	PMID:475|RGD:2326214
Biological Process	GO:0045471	response to ethanol	Oxct1	IEP		Rat	PMID:8104400|RGD:2301024
Biological Process	GO:0009725	response to hormone	Oxct1	IEP		Rat	PMID:6144148|RGD:4105445
Biological Process	GO:0007584	response to nutrient	Oxct1	IEP		Rat	PMID:20025965|RGD:2326188
Biological Process	GO:0042594	response to starvation	Oxct1	IEP		Rat	PMID:2985752|RGD:2326102
Biological Process	GO:0009410	response to xenobiotic stimulus	Oxct1	IEP		Rat	PMID:17283165|RGD:2326194

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern