Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OTUD5
  • Mouse genes Otud5
  • Rat genes Otud5
  • Zfish genes otud5a,otud5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Otud5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	OTUD5	IDA		Human	PMID:22245969
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	OTUD5	IDA		Human	PMID:23827681
Molecular Function	GO:0101005	deubiquitinase activity	OTUD5	IDA		Human	PMID:22245969
Molecular Function	GO:0101005	deubiquitinase activity	OTUD5	IMP		Human	PMID:33110214
Molecular Function	GO:1990380	K48-linked deubiquitinase activity	OTUD5	IDA		Human	PMID:22245969
Molecular Function	GO:1990380	K48-linked deubiquitinase activity	OTUD5	IMP		Human	PMID:33523931
Molecular Function	GO:0061578	K63-linked deubiquitinase activity	OTUD5	EXP		Human	PMID:17991829
Molecular Function	GO:0061578	K63-linked deubiquitinase activity	OTUD5	IDA		Human	PMID:22245969
Molecular Function	GO:0061578	K63-linked deubiquitinase activity	OTUD5	IMP		Human	PMID:33523931
Molecular Function	GO:0005515	protein binding	Otud5	IPI	PR:Q80TP3	Mouse	PMID:25470037
Cellular Component	GO:0005634	nucleus	OTUD5	IDA		Human	PMID:33523931
Biological Process	GO:0043374	CD8-positive, alpha-beta T cell differentiation	Otud5	IMP	MGI:MGI:2386448,MGI:MGI:5752247	Mouse	PMID:25470037
Biological Process	GO:0032625	interleukin-21 production	Otud5	IMP	MGI:MGI:2386448,MGI:MGI:5752247	Mouse	PMID:25470037
Biological Process	GO:0032638	interleukin-9 production	Otud5	IMP	MGI:MGI:2386448,MGI:MGI:5752247	Mouse	PMID:25470037
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	OTUD5	IMP		Human	PMID:33110214
Biological Process	GO:0032700	negative regulation of interleukin-17 production	Otud5	IMP	MGI:MGI:2386448,MGI:MGI:5752247	Mouse	PMID:25470037
Biological Process	GO:0032700	negative regulation of interleukin-17 production	Otud5	IGI	MGI:MGI:1918040	Mouse	PMID:25470037
Biological Process	GO:0014033	neural crest cell differentiation	OTUD5	IMP		Human	PMID:33523931
Biological Process	GO:1904263	positive regulation of TORC1 signaling	OTUD5	IMP		Human	PMID:33110214
Biological Process	GO:1904515	positive regulation of TORC2 signaling	OTUD5	IMP		Human	PMID:33110214
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Otud5	IMP	MGI:MGI:2386448,MGI:MGI:5752247	Mouse	PMID:25470037
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Otud5	IDA		Mouse	PMID:25470037
Biological Process	GO:0016579	protein deubiquitination	OTUD5	IDA		Human	PMID:22245969
Biological Process	GO:0016579	protein deubiquitination	OTUD5	IMP		Human	PMID:33110214
Biological Process	GO:0071108	protein K48-linked deubiquitination	OTUD5	IDA		Human	PMID:22245969
Biological Process	GO:0071108	protein K48-linked deubiquitination	OTUD5	IDA		Human	PMID:23827681
Biological Process	GO:0071108	protein K48-linked deubiquitination	OTUD5	IMP		Human	PMID:33523931
Biological Process	GO:0070536	protein K63-linked deubiquitination	OTUD5	IDA		Human	PMID:22245969
Biological Process	GO:0070536	protein K63-linked deubiquitination	OTUD5	IDA		Human	PMID:23827681
Biological Process	GO:0070536	protein K63-linked deubiquitination	OTUD5	IMP		Human	PMID:33523931
Biological Process	GO:0031647	regulation of protein stability	Otud5	IMP	MGI:MGI:2386448,MGI:MGI:5752247	Mouse	PMID:25470037
Biological Process	GO:2000316	regulation of T-helper 17 type immune response	Otud5	IMP	MGI:MGI:2386448,MGI:MGI:5752247	Mouse	PMID:25470037
Biological Process	GO:0032496	response to lipopolysaccharide	OTUD5	IDA		Human	PMID:22245969
Biological Process	GO:0072540	T-helper 17 cell lineage commitment	Otud5	IMP	MGI:MGI:2386448,MGI:MGI:5752247	Mouse	PMID:25470037

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern