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Otud5 Gene Detail
Summary
  • Symbol
    Otud5
  • Name
    OTU domain containing 5
  • Synonyms
    Duba, DXImx46e, Sfc7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859615
    NCBI Gene: 54644
Location & Maps
more
  • Genetic Map
    Chromosome X, 3.54 cM
  • Mapping Data
    4 experiments
Homology
less
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    2 images
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    11
  • Gene trapped
    8
  • Targeted
    3
Male chimeras hemizygous for a gene trapped allele exhibit abnormalities in developmental patterning and embryo turning.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017928 VEGA Gene Model | MGI Sequence Detail 35263 C57BL/6J ±  kb
transcript OTTMUST00000043469 VEGA | MGI Sequence Detail 2708 Not Applicable  
polypeptide OTTMUSP00000019531 VEGA | MGI Sequence Detail 571 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    106 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000012082 OTU domain-containing protein 5
  • EC
  • InterPro Domains
    IPR003323 OTU domain
    IPR031084 OTU domain-containing protein 5/Otubain-like deubiquitinase 1
Molecular
Reagents
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  • All nucleic 18
    Genomic 3
    cDNA 15

    Microarray probesets 8
Other
Accession IDs
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MGI:2147820, MGI:2147900, MGI:2148034
References
more
  • Summaries
    All 35
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:62168 Means GD, et al., A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation. Genomics. 2000 May 1;65(3):213-23
  • Latest
    J:219495 Rutz S, et al., Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature. 2015 Feb 19;518(7539):417-21

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory