Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OSTN
  • Mouse genes Ostn
  • Rat genes Ostn
  • Zfish genes ostn
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ostn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005102	signaling receptor binding	Ostn	IDA		Mouse	PMID:17951249
Cellular Component	GO:0005615	extracellular space	Ostn	IDA		Mouse	PMID:15044443
Cellular Component	GO:0005615	extracellular space	Ostn	IDA		Mouse	PMID:14523025
Biological Process	GO:0051216	cartilage development	ostn	IMP	ZFIN:ZDB-GENO-170928-7	Zfish	PMID:27993976
Biological Process	GO:0007166	cell surface receptor signaling pathway	Ostn	IDA		Mouse	PMID:17951249
Biological Process	GO:0003416	endochondral bone growth	Ostn	IDA		Mouse	PMID:17951249
Biological Process	GO:0001958	endochondral ossification	ostn	IMP	ZFIN:ZDB-GENO-170928-7	Zfish	PMID:27993976
Biological Process	GO:0009755	hormone-mediated signaling pathway	Ostn	IDA		Mouse	PMID:17951249
Biological Process	GO:1903860	negative regulation of dendrite extension	OSTN	IMP		Human	PMID:27830782
Biological Process	GO:0046325	negative regulation of glucose import	Ostn	IDA		Mouse	PMID:15044443
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	Ostn	IDA		Mouse	PMID:14523025

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern