Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OSBP
  • Mouse genes Osbp
  • Rat genes Osbp
  • Zfish genes osbp
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Osbp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	OSBP	IDA		Human	PMID:24209621
Molecular Function	GO:0005515	protein binding	OSBP	IPI	UniProtKB:A0A0H3NDL6	Human	PMID:21566117
Molecular Function	GO:0005515	protein binding	OSBP	IPI	UniProtKB:Q8ZNG2	Human	PMID:21988961
Molecular Function	GO:0005515	protein binding	OSBP	IPI	UniProtKB:Q9P0L0	Human	PMID:24209621
Molecular Function	GO:0005515	protein binding	OSBP	IPI	UniProtKB:O75344	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	OSBP	IPI	UniProtKB:Q9P0L0	Human	PMID:25681634
Molecular Function	GO:0005515	protein binding	OSBP	IPI	UniProtKB:Q9P0L0	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	OSBP	IPI	UniProtKB:O75344	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	OSBP	IPI	UniProtKB:Q92685	Human	PMID:29547901
Molecular Function	GO:0005515	protein binding	OSBP	IPI	UniProtKB:Q9P0L0	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	OSBP	IPI	UniProtKB:Q9P0L0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Osbp	IPI	UniProtKB:Q148V7	Mouse	MGI:MGI:6155399|PMID:29514919
Molecular Function	GO:0019904	protein domain specific binding	OSBP	IPI	UniProtKB:Q9P0L0	Human	PMID:20178991
Molecular Function	GO:0120015	sterol transfer activity	OSBP	IDA		Human	PMID:24209621
Cellular Component	GO:0030054	cell junction	OSBP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	OSBP	IDA		Human	PMID:21988961
Cellular Component	GO:0005829	cytosol	OSBP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	OSBP	IDA		Human	PMID:24209621
Cellular Component	GO:0005829	cytosol	OSBP	IDA		Human	PMID:29514919
Cellular Component	GO:0005829	cytosol	Osbp	IDA		Rat	PMID:18230613|RGD:2291921
Cellular Component	GO:0005789	endoplasmic reticulum membrane	OSBP	IDA		Human	PMID:12023275
Cellular Component	GO:0005794	Golgi apparatus	OSBP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000139	Golgi membrane	OSBP	IDA		Human	PMID:24209621
Cellular Component	GO:0016020	membrane	OSBP	IDA		Human	PMID:21988961
Cellular Component	GO:0005730	nucleolus	OSBP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	OSBP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0048471	perinuclear region of cytoplasm	OSBP	IDA		Human	PMID:24209621
Cellular Component	GO:0005802	trans-Golgi network	OSBP	IDA		Human	PMID:29514919
Biological Process	GO:0035627	ceramide transport	OSBP	IMP		Human	PMID:12023275
Biological Process	GO:0032367	intracellular cholesterol transport	OSBP	IMP		Human	PMID:29514919
Biological Process	GO:0015914	phospholipid transport	OSBP	IDA		Human	PMID:24209621
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Osbp	IMP		Rat	PMID:29540530|RGD:41404656
Biological Process	GO:1904411	positive regulation of secretory granule organization	Osbp	IMP		Rat	PMID:29540530|RGD:41404656
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	Osbp	IMP		Rat	PMID:18230613|RGD:2291921
Biological Process	GO:0006686	sphingomyelin biosynthetic process	OSBP	IMP		Human	PMID:12023275
Biological Process	GO:0015918	sterol transport	OSBP	IDA		Human	PMID:24209621

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern