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Osbp Gene Detail
Summary
  • Symbol
    Osbp
  • Name
    oxysterol binding protein
  • Synonyms
    1110018F06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:97447
    NCBI Gene: 76303
  • Gene Overview
    MyGene.info: OSBP
Location & Maps
more
  • Sequence Map
    Chr19:11965844-11994105 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      28262 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 8.58 cM
  • Mapping Data
    12 experiments
Homology
more
  • Human Ortholog
    OSBP, oxysterol binding protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    OSBP, oxysterol binding protein
    Orthology source: HomoloGene
  • Synonyms
    OSBP1
  • Links
    NCBI Gene ID: 5007
    neXtProt AC: NX_P22059

  • Chr Location
    11q12-q13; chr11:59574398-59616144 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 97668
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: OSBP
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    7
  • Gene trapped
    4
  • Targeted
    3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024687 Ensembl Gene Model | MGI Sequence Detail 28262 C57BL/6J ±  kb
transcript ENSMUST00000025590 Ensembl | MGI Sequence Detail 4578 Not Applicable  
polypeptide ENSMUSP00000025590 Ensembl | MGI Sequence Detail 805 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    164 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000012043 oxysterol-binding protein 1
  • InterPro Domains
    IPR000648 Oxysterol-binding protein
    IPR018494 Oxysterol-binding protein, conserved site
    IPR011993 PH domain-like
    IPR001849 Pleckstrin homology domain
Molecular
Reagents
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  • All nucleic 17
    cDNA 16
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
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MGD-MRK-13055, MGI:1923553, MGI:2147753
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:10477 Levanon D, et al., cDNA cloning of human oxysterol-binding protein and localization of the gene to human chromosome 11 and mouse chromosome 19. Genomics. 1990 May;7(1):65-74
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory