Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OFD1
  • Mouse genes Ofd1
  • Rat genes Ofd1
  • Zfish genes ofd1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ofd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043014	alpha-tubulin binding	Ofd1	IDA		Mouse	MGI:MGI:4457459|PMID:20230748
Molecular Function	GO:0043015	gamma-tubulin binding	Ofd1	IDA		Mouse	MGI:MGI:4457459|PMID:20230748
Molecular Function	GO:0042802	identical protein binding	OFD1	IPI	UniProtKB:O75665	Human	PMID:17761535
Molecular Function	GO:0060090	molecular adaptor activity	OFD1	IMP		Human	PMID:19800048
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:Q9Y265	Human	PMID:17761535
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:Q86VQ0	Human	PMID:19800048
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:Q86SQ7	Human	PMID:20835237
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:P53350	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:Q9Y5B8	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:Q96ST8	Human	PMID:23789104
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:Q15154	Human	PMID:24089205
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:Q9GZQ8	Human	PMID:24089205
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:Q4AC94	Human	PMID:24997988
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:Q15154	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:Q4AC94	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:P53350	Human	PMID:26638075
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:Q15154	Human	PMID:26638075
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:Q9Y5B8	Human	PMID:26638075
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:O75143	Human	PMID:33368531
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:Q9GZQ8	Human	PMID:33368531
Molecular Function	GO:0005515	protein binding	OFD1	IPI	UniProtKB:Q96DN5	Human	PMID:33934390
Cellular Component	GO:0034451	centriolar satellite	Ofd1	IDA		Mouse	MGI:MGI:5527013|PMID:24089205
Cellular Component	GO:0034451	centriolar satellite	Ofd1	IDA		Mouse	PMID:24469809
Cellular Component	GO:0005814	centriole	OFD1	IDA		Human	PMID:20230748
Cellular Component	GO:0005814	centriole	Ofd1	IDA		Mouse	MGI:MGI:5527013|PMID:24089205
Cellular Component	GO:0005814	centriole	Ofd1	IDA		Mouse	MGI:MGI:4457459|PMID:20230748
Cellular Component	GO:0005814	centriole	Ofd1	IDA		Mouse	PMID:29487109
Cellular Component	GO:0005813	centrosome	OFD1	IDA		Human	PMID:21399614
Cellular Component	GO:0005813	centrosome	OFD1	IDA		Human	PMID:33934390
Cellular Component	GO:0005813	centrosome	ofd1	IDA		Zfish	PMID:18971206
Cellular Component	GO:0036064	ciliary basal body	OFD1	IDA		Human	PMID:33934390
Cellular Component	GO:0036064	ciliary basal body	OFD1	IDA		Human	PMID:20230748
Cellular Component	GO:0036064	ciliary basal body	Ofd1	IDA		Mouse	MGI:MGI:4457459|PMID:20230748
Cellular Component	GO:0036064	ciliary basal body	ofd1	IDA		Zfish	PMID:18971206
Cellular Component	GO:0005929	cilium	OFD1	IDA		Human	PMID:20230748
Cellular Component	GO:0005929	cilium	Ofd1	IDA		Mouse	MGI:MGI:4457459|PMID:20230748
Cellular Component	GO:0005576	extracellular region	ofd1	IMP	ZFIN:ZDB-MRPHLNO-090407-1	Zfish	PMID:18971206|ZFIN:ZDB-PUB-081031-7
Cellular Component	GO:0016020	membrane	OFD1	HDA		Human	PMID:19946888
Cellular Component	GO:0015630	microtubule cytoskeleton	OFD1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ofd1	IDA		Zfish	PMID:18971206
Biological Process	GO:0035082	axoneme assembly	Ofd1	IMP	MGI:MGI:3620081	Mouse	PMID:16311594
Biological Process	GO:0060271	cilium assembly	OFD1	IMP		Human	PMID:33934390
Biological Process	GO:0060271	cilium assembly	Ofd1	IDA		Mouse	MGI:MGI:4457459|PMID:20230748
Biological Process	GO:0060271	cilium assembly	Ofd1	IMP		Mouse	MGI:MGI:3617259|PMID:16311594
Biological Process	GO:0060271	cilium assembly	Ofd1	IMP		Rat	PMID:27196396|RGD:11535964
Biological Process	GO:0060026	convergent extension	ofd1	IMP	ZFIN:ZDB-MRPHLNO-090312-2	Zfish	PMID:24691443
Biological Process	GO:0060027	convergent extension involved in gastrulation	ofd1	IMP	ZFIN:ZDB-MRPHLNO-090407-2	Zfish	PMID:18971206
Biological Process	GO:0060027	convergent extension involved in gastrulation	ofd1	IGI	ZFIN:ZDB-GENO-070305-2,ZFIN:ZDB-MRPHLNO-090312-2	Zfish	PMID:18971206
Biological Process	GO:0060027	convergent extension involved in gastrulation	ofd1	IGI	ZFIN:ZDB-MRPHLNO-041217-10,ZFIN:ZDB-MRPHLNO-090312-2	Zfish	PMID:18971206
Biological Process	GO:0060027	convergent extension involved in gastrulation	ofd1	IMP	ZFIN:ZDB-MRPHLNO-090312-2	Zfish	PMID:18971206
Biological Process	GO:0060027	convergent extension involved in gastrulation	ofd1	IGI	ZFIN:ZDB-MRPHLNO-041217-5,ZFIN:ZDB-MRPHLNO-090312-2	Zfish	PMID:18971206
Biological Process	GO:0060027	convergent extension involved in gastrulation	ofd1	IMP	ZFIN:ZDB-MRPHLNO-090407-1	Zfish	PMID:18971206
Biological Process	GO:0061371	determination of heart left/right asymmetry	ofd1	IGI	ZFIN:ZDB-MRPHLNO-060208-1,ZFIN:ZDB-MRPHLNO-090312-2	Zfish	PMID:21266464
Biological Process	GO:0061371	determination of heart left/right asymmetry	ofd1	IMP	ZFIN:ZDB-MRPHLNO-090312-2	Zfish	PMID:21266464
Biological Process	GO:0010172	embryonic body morphogenesis	Ofd1	IMP		Mouse	MGI:MGI:5498583|PMID:23806618
Biological Process	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	Ofd1	IMP		Mouse	MGI:MGI:3617259|PMID:16311594
Biological Process	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	ofd1	IMP	ZFIN:ZDB-MRPHLNO-090407-2	Zfish	PMID:18971206
Biological Process	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	ofd1	IMP	ZFIN:ZDB-MRPHLNO-090312-2	Zfish	PMID:18971206
Biological Process	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	ofd1	IMP	ZFIN:ZDB-MRPHLNO-090407-1	Zfish	PMID:18971206
Biological Process	GO:2000314	negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	Ofd1	IMP		Mouse	MGI:MGI:5498583|PMID:23806618

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern