Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Nrp2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes NRP2
- Mouse genes Nrp2
- Rat genes Nrp2
- Zfish genes nrp2a,nrp2b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nrp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	nrp2a	IDA		Zfish	PMID:25656526
Molecular Function	GO:0005515	protein binding	NRP2	IPI	UniProtKB:P97953-1	Human	PMID:25752543
Molecular Function	GO:0005515	protein binding	Nrp2	IPI	UniProtKB:Q4LFA9	Mouse	MGI:MGI:3619679\|PMID:16098142
Molecular Function	GO:0005515	protein binding	Nrp2	IPI	PR:Q62181	Mouse	PMID:15239958
Molecular Function	GO:0005515	protein binding	Nrp2	IPI	PR:P70206	Mouse	PMID:10520994
Molecular Function	GO:0005515	protein binding	nrp2a	IPI	RefSeq:NM_017310	Zfish	PMID:25656526
Molecular Function	GO:0017154	semaphorin receptor activity	Nrp2	IDA		Mouse	PMID:15239958
Cellular Component	GO:0030424	axon	Nrp2	IDA		Mouse	PMID:15677725
Cellular Component	GO:0098978	glutamatergic synapse	Nrp2	IDA		Mouse	PMID:25143608
Cellular Component	GO:0098978	glutamatergic synapse	Nrp2	IDA		Mouse	PMID:20010807
Cellular Component	GO:0098978	glutamatergic synapse	Nrp2	IMP		Mouse	PMID:20010807
Cellular Component	GO:0045211	postsynaptic membrane	Nrp2	IDA		Mouse	PMID:25143608
Biological Process	GO:0048846	axon extension involved in axon guidance	Nrp2	IMP		Mouse	MGI:MGI:5437554\|PMID:22790009
Biological Process	GO:0007411	axon guidance	Nrp2	IMP		Mouse	PMID:15814794
Biological Process	GO:0007411	axon guidance	Nrp2	IEP		Rat	PMID:9288754\|RGD:633436
Biological Process	GO:0007411	axon guidance	nrp2b	IMP		Zfish	PMID:15456815
Biological Process	GO:0007413	axonal fasciculation	nrp2b	IMP		Zfish	PMID:15456815
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Nrp2	IEP		Mouse	PMID:20439489
Biological Process	GO:1904835	dorsal root ganglion morphogenesis	Nrp2	IMP		Mouse	MGI:MGI:3848580\|PMID:19386662
Biological Process	GO:0021612	facial nerve structural organization	Nrp2	IMP		Mouse	MGI:MGI:3788968\|PMID:18356247
Biological Process	GO:1903375	facioacoustic ganglion development	Nrp2	IMP		Mouse	MGI:MGI:3788968\|PMID:18356247
Biological Process	GO:0021828	gonadotrophin-releasing hormone neuronal migration to the hypothalamus	Nrp2	IMP		Mouse	MGI:MGI:4850173\|PMID:21059704
Biological Process	GO:0007507	heart development	Nrp2	IGI	MGI:MGI:106206	Mouse	PMID:12852851
Biological Process	GO:0050919	negative chemotaxis	Nrp2	IGI	MGI:MGI:1096347	Mouse	PMID:16319111
Biological Process	GO:0050919	negative chemotaxis	Nrp2	IMP		Mouse	PMID:15814794
Biological Process	GO:0021675	nerve development	Nrp2	IMP		Mouse	MGI:MGI:5437554\|PMID:22790009
Biological Process	GO:0001755	neural crest cell migration	nrp2a	IGI	ZFIN:ZDB-GENO-071026-2,ZFIN:ZDB-MRPHLNO-050513-10	Zfish	PMID:15882579
Biological Process	GO:0001755	neural crest cell migration	nrp2b	IGI	ZFIN:ZDB-GENO-071026-2,ZFIN:ZDB-MRPHLNO-050513-11	Zfish	PMID:15882579
Biological Process	GO:1901166	neural crest cell migration involved in autonomic nervous system development	Nrp2	IMP		Mouse	MGI:MGI:3788968\|PMID:18356247
Biological Process	GO:1901166	neural crest cell migration involved in autonomic nervous system development	Nrp2	IMP		Mouse	MGI:MGI:3848580\|PMID:19386662
Biological Process	GO:0001764	neuron migration	Nrp2	IMP		Mouse	MGI:MGI:4850173\|PMID:21059704
Biological Process	GO:0071678	olfactory bulb axon guidance	nrp2b	IMP	ZFIN:ZDB-GENO-200504-8	Zfish	PMID:26732841
Biological Process	GO:0071678	olfactory bulb axon guidance	nrp2b	IGI	ZFIN:ZDB-GENE-990715-2	Zfish	PMID:26732841
Biological Process	GO:0003148	outflow tract septum morphogenesis	Nrp2	IGI	UniProtKB:Q62181	Mouse	MGI:MGI:5693177\|PMID:26053665
Biological Process	GO:0099175	regulation of postsynapse organization	Nrp2	IDA		Mouse	PMID:20010807
Biological Process	GO:0099175	regulation of postsynapse organization	Nrp2	IMP		Mouse	PMID:20010807
Biological Process	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	nrp2a	IMP		Zfish	PMID:15305285
Biological Process	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	nrp2b	IMP		Zfish	PMID:15305285
Biological Process	GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	Nrp2	IMP		Mouse	MGI:MGI:5437554\|PMID:22790009
Biological Process	GO:0097374	sensory neuron axon guidance	Nrp2	IMP		Mouse	MGI:MGI:3788968\|PMID:18356247
Biological Process	GO:0061549	sympathetic ganglion development	Nrp2	IMP		Mouse	MGI:MGI:5437554\|PMID:22790009
Biological Process	GO:0097490	sympathetic neuron projection extension	Nrp2	IMP		Mouse	MGI:MGI:5437554\|PMID:22790009
Biological Process	GO:0097491	sympathetic neuron projection guidance	Nrp2	IMP		Mouse	MGI:MGI:5437554\|PMID:22790009
Biological Process	GO:0061551	trigeminal ganglion development	Nrp2	IMP		Mouse	MGI:MGI:3788968\|PMID:18356247
Biological Process	GO:0036484	trunk neural crest cell migration	Nrp2	IMP	MGI:MGI:2137037	Mouse	PMID:16319111
Biological Process	GO:0001570	vasculogenesis	nrp2a	IMP		Zfish	PMID:15305285
Biological Process	GO:0001570	vasculogenesis	nrp2b	IMP		Zfish	PMID:15305285
Biological Process	GO:0036486	ventral trunk neural crest cell migration	Nrp2	IMP		Mouse	MGI:MGI:3848580\|PMID:19386662
Biological Process	GO:0021649	vestibulocochlear nerve structural organization	Nrp2	IMP		Mouse	MGI:MGI:3788968\|PMID:18356247

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.