Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NPFF
  • Mouse genes Npff
  • Rat genes Npff
  • Zfish genes npffl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Npff

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001664	G protein-coupled receptor binding	Npff	IDA		Rat	PMID:11024015|RGD:633416
Molecular Function	GO:0005184	neuropeptide hormone activity	Npff	IDA		Rat	PMID:11984823|RGD:633355
Cellular Component	GO:0043679	axon terminus	Npff	IDA		Rat	PMID:1924889|RGD:2316577
Cellular Component	GO:0030425	dendrite	Npff	IDA		Rat	PMID:1924889|RGD:2316577
Cellular Component	GO:0005615	extracellular space	Npff	IDA		Rat	PMID:7891084|RGD:2316576
Cellular Component	GO:0098992	neuronal dense core vesicle	Npff	IDA		Rat	PMID:1924889|RGD:2316577
Cellular Component	GO:0043204	perikaryon	Npff	IDA		Rat	PMID:1924889|RGD:2316577
Cellular Component	GO:0031982	vesicle	Npff	IDA		Rat	PMID:1924889|RGD:2316577
Biological Process	GO:0002438	acute inflammatory response to antigenic stimulus	Npff	IEP		Rat	PMID:15207282|RGD:2316569
Biological Process	GO:0060079	excitatory postsynaptic potential	Npff	IDA		Rat	PMID:10938301|RGD:2316571
Biological Process	GO:0060135	maternal process involved in female pregnancy	Npff	IEP		Rat	PMID:12619141|RGD:1299340
Biological Process	GO:0032099	negative regulation of appetite	Npff	IDA		Rat	PMID:8801545|RGD:2316575
Biological Process	GO:0010459	negative regulation of heart rate	Npff	IDA		Rat	PMID:8680863|RGD:2316573
Biological Process	GO:0046676	negative regulation of insulin secretion	Npff	IDA		Rat	PMID:1704109|RGD:2316580
Biological Process	GO:0045777	positive regulation of blood pressure	Npff	IDA		Rat	PMID:8680863|RGD:2316573
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Npff	IDA		Rat	PMID:11024015|RGD:633416
Biological Process	GO:0003254	regulation of membrane depolarization	Npff	IDA		Rat	PMID:17289819|RGD:2316567
Biological Process	GO:0051930	regulation of sensory perception of pain	Npff	IDA		Rat	PMID:17980934|RGD:2316566
Biological Process	GO:0043278	response to morphine	Npff	IEP		Rat	PMID:15207282|RGD:2316569
Biological Process	GO:0009410	response to xenobiotic stimulus	Npff	IEP		Rat	PMID:16529722|RGD:2316568
Biological Process	GO:0070253	somatostatin secretion	Npff	IDA		Rat	PMID:1704109|RGD:2316580
Biological Process	GO:0021510	spinal cord development	Npff	IEP		Rat	PMID:12619141|RGD:1299340
Biological Process	GO:0030103	vasopressin secretion	Npff	IDA		Rat	PMID:8612481|RGD:2316572

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern