Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NMNAT1
  • Mouse genes Nmnat1
  • Rat genes Nmnat1
  • Zfish genes nmnat1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nmnat1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	NMNAT1	IPI	UniProtKB:Q9HAN9	Human	PMID:21516116
Molecular Function	GO:0042802	identical protein binding	NMNAT1	IPI	UniProtKB:Q9HAN9	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	NMNAT1	IPI	UniProtKB:Q9HAN9	Human	PMID:25502805
Molecular Function	GO:0042802	identical protein binding	NMNAT1	IPI	UniProtKB:Q9HAN9	Human	PMID:31515488
Molecular Function	GO:0042802	identical protein binding	NMNAT1	IPI	UniProtKB:Q9HAN9	Human	PMID:32296183
Molecular Function	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity	NMNAT1	IDA		Human	PMID:11027696
Molecular Function	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity	Nmnat1	IDA		Mouse	PMID:16914673
Molecular Function	GO:0004515	nicotinate-nucleotide adenylyltransferase activity	NMNAT1	IDA		Human	PMID:16118205
Molecular Function	GO:0004515	nicotinate-nucleotide adenylyltransferase activity	Nmnat1	IDA		Mouse	PMID:15381699
Molecular Function	GO:0140768	protein ADP-ribosyltransferase-substrate adaptor activity	Nmnat1	IDA		Mouse	PMID:32822587
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:P09874	Human	PMID:11248244
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:Q96EB6	Human	PMID:19478080
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:P48775	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:P24863	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:P52292	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:A0A0S2Z5G4	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:B4DE54	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:Q8N9N5-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:P24863	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:P52292	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:O00505	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:O15131	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:O60684	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:P48775	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:P52292	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:P52294	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:P78317	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:Q8N9N5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:Q8NCF5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:Q9H8Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NMNAT1	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Cellular Component	GO:0000785	chromatin	Nmnat1	IDA		Mouse	PMID:32822587
Cellular Component	GO:0005737	cytoplasm	Nmnat1	IDA		Rat	PMID:27184051|RGD:13781945
Cellular Component	GO:0016604	nuclear body	NMNAT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NMNAT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NMNAT1	IDA		Human	PMID:11248244
Cellular Component	GO:0005634	nucleus	NMNAT1	IDA		Human	PMID:16118205
Cellular Component	GO:0005634	nucleus	NMNAT1	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	Nmnat1	IDA		Mouse	PMID:15381699
Cellular Component	GO:0005634	nucleus	Nmnat1	IDA		Mouse	PMID:16914673
Cellular Component	GO:0005634	nucleus	Nmnat1	IDA		Rat	PMID:27184051|RGD:13781945
Biological Process	GO:1990966	ATP generation from poly-ADP-D-ribose	NMNAT1	IDA		Human	PMID:27257257
Biological Process	GO:0009435	NAD biosynthetic process	Nmnat1	IMP		Mouse	MGI:MGI:6206974|PMID:27735788
Biological Process	GO:0009435	NAD biosynthetic process	Nmnat1	IDA		Mouse	PMID:16914673
Biological Process	GO:0009435	NAD biosynthetic process	Nmnat1	IDA		Mouse	PMID:15381699
Biological Process	GO:1902511	negative regulation of apoptotic DNA fragmentation	Nmnat1	IMP		Rat	PMID:27184051|RGD:13781945
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nmnat1	IDA		Mouse	PMID:32822587
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Nmnat1	IMP		Rat	PMID:27184051|RGD:13781945
Biological Process	GO:1901215	negative regulation of neuron death	Nmnat1	IMP		Mouse	MGI:MGI:6206974|PMID:27735788
Biological Process	GO:0043410	positive regulation of MAPK cascade	Nmnat1	IMP		Rat	PMID:27184051|RGD:13781945
Biological Process	GO:0009611	response to wounding	Nmnat1	IDA		Mouse	PMID:16914673

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern