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Nmnat1
Gene Detail
Symbol

Name
ID
Nmnat1
nicotinamide nucleotide adenylyltransferase 1
MGI:1913704
Synonyms
2610529L11Rik, 5730441G13Rik, D4Cole1e, nicotinamide mononucleotide adenylyl transferase, nmnat
Feature Type
protein coding gene
Genetic Map
Chromosome 4
79.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:149467572-149485202 bp, - strand
From VEGA annotation of GRCm38

  17631 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:39074  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: NMNAT1
Gene Tree: Nmnat1

Human
homologs
NMNAT1, nicotinamide nucleotide adenylyltransferase 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 64802
neXtProt AC: NX_Q9HAN9

Human Synonyms: LCA9, NMNAT, PNAT1

Human Chr (Location): 1p36.22; chr1:9942923-9985501 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human NMNAT1

Mutations,
alleles, and
phenotypes
All mutations/alleles(25) : Gene trapped(19) Spontaneous(1) Targeted(5)
Genomic Mutations involving Nmnat1 (2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit complete prenatal lethality.
 
Interactions
Nmnat1 interacts with 196 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(20)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase nmnat1 ; ZFIN nmnat1    NEW 
Molecular
reagents
All nucleic(24) Genomic(1) cDNA(23)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000010262 (Evidence)
Ensembl Gene Model ENSMUSG00000028992 (Evidence)
Entrez Gene 66454 (Evidence)
UniGene 76062
Consensus CDS Project CCDS18960.1
International Mouse Phenotyping Consortium Status Nmnat1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010262 VEGA Gene Model | MGI Sequence Detail 17631 C57BL/6J ±  kb
transcript OTTMUST00000023867 VEGA | MGI Sequence Detail 1238 Not Applicable 
polypeptide OTTMUSP00000010940 VEGA | MGI Sequence Detail 285 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(6)
Polymorphisms
SNPs within 2kb(167 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000011290 nicotinamide mononucleotide adenylyltransferase 1
References
(Earliest) J:65178 Conforti L, et al., A Ufd2/D4Cole1e chimeric protein and overexpression of rbp7 in the slow wallerian degeneration (WldS) mouse. Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11377-82
(Latest) J:200901 Gilley J, et al., Rescue of Peripheral and CNS Axon Defects in Mice Lacking NMNAT2. J Neurosci. 2013 Aug 14;33(33):13410-24
All references(43)
Other
accession IDs
MGI:1917803, MGI:1927087

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory