Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NLE1
  • Mouse genes Nle1
  • Rat genes Nle1
  • Zfish genes nle1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nle1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0005730	nucleolus	NLE1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	Nle1	IDA		Mouse	PMID:24081661
Cellular Component	GO:0005654	nucleoplasm	NLE1	IDA		Human	GO_REF:0000052
Biological Process	GO:0061484	hematopoietic stem cell homeostasis	Nle1	IMP	MGI:MGI:3624778	Mouse	PMID:24062412
Biological Process	GO:0001826	inner cell mass cell differentiation	Nle1	IMP	MGI:MGI:3624778	Mouse	PMID:16611995
Biological Process	GO:0001822	kidney development	Nle1	IMP	MGI:MGI:2176174,MGI:MGI:5553357	Mouse	PMID:24875805
Biological Process	GO:0000278	mitotic cell cycle	Nle1	IMP	MGI:MGI:3624778	Mouse	PMID:24062412
Biological Process	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Nle1	IMP	MGI:MGI:2671871	Mouse	PMID:23231322
Biological Process	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Nle1	IMP	MGI:MGI:2671874	Mouse	PMID:23231322
Biological Process	GO:0045930	negative regulation of mitotic cell cycle	Nle1	IMP	MGI:MGI:3624778	Mouse	PMID:24062412
Biological Process	GO:0007219	Notch signaling pathway	Nle1	IDA		Mouse	PMID:16611995
Biological Process	GO:0007219	Notch signaling pathway	Nle1	IMP	MGI:MGI:2671871	Mouse	PMID:23231322
Biological Process	GO:0007219	Notch signaling pathway	Nle1	IMP	MGI:MGI:2671874	Mouse	PMID:23231322
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	Nle1	IMP	MGI:MGI:2671871	Mouse	PMID:23231322
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	Nle1	IMP	MGI:MGI:2671874	Mouse	PMID:23231322
Biological Process	GO:0042273	ribosomal large subunit biogenesis	Nle1	IMP	MGI:MGI:3624778	Mouse	PMID:24062412
Biological Process	GO:0048705	skeletal system morphogenesis	Nle1	IMP	MGI:MGI:2176174,MGI:MGI:5553357	Mouse	PMID:24824078
Biological Process	GO:0001756	somitogenesis	Nle1	IMP	MGI:MGI:2176174,MGI:MGI:5553357	Mouse	PMID:24875805

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern