Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NFX1
  • Mouse genes Nfx1
  • Rat genes Nfx1
  • Zfish genes nfx1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nfx1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	NFX1	IDA		Human	PMID:7964459
Molecular Function	GO:0005515	protein binding	NFX1	IPI	UniProtKB:G5E9A7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NFX1	IPI	UniProtKB:P02545	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NFX1	IPI	UniProtKB:P14136	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NFX1	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NFX1	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NFX1	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NFX1	IPI	UniProtKB:Q86WV8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Nfx1	IPI	PR:Q9JL10	Mouse	PMID:11331592
Molecular Function	GO:0005515	protein binding	Nfx1	IPI	PR:Q9JJG5	Mouse	PMID:11331592
Molecular Function	GO:0003723	RNA binding	NFX1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	NFX1	HDA		Human	PMID:22681889
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	NFX1	IDA		Human	PMID:7964459
Molecular Function	GO:0061630	ubiquitin protein ligase activity	NFX1	IDA		Human	PMID:10500182
Cellular Component	GO:0005829	cytosol	NFX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	NFX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NFX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	NFX1	IDA		Human	GO_REF:0000052
Biological Process	GO:0045347	negative regulation of MHC class II biosynthetic process	Nfx1	IDA		Mouse	PMID:12047746
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	NFX1	IDA		Human	PMID:7964459
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nfx1	IDA		Mouse	PMID:12047746
Biological Process	GO:0051865	protein autoubiquitination	NFX1	IDA		Human	PMID:10500182

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern