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Nfx1
Gene Detail
Symbol

Name
ID
Nfx1
nuclear transcription factor, X-box binding 1
MGI:1921414
Synonyms
1300017N15Rik, 3000003M19Rik, TEG-42, Tex42
Feature Type
protein coding gene
Genetic Map
Chromosome 4
20.72 cM, cytoband B1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:40970906-41025993 bp, + strand
From VEGA annotation of GRCm38

  55088 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1875  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: NFX1
Gene Tree: Nfx1

Human
homologs
NFX1, nuclear transcription factor, X-box binding 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 4799
neXtProt AC: NX_Q12986

Human Synonyms: NFX2, TEG-42, Tex42

Human Chr (Location): 9p13.3; chr9:33290420-33371157 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(56) : Gene trapped(54) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Nfx1 interacts with 249 markers (Mir1b, Mir10a, Mir15a, ...)
Expression
Literature Summary: (4 records)
Data Summary: Results (17)    Tissues (17)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 17
cDNA source data(18)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase nfx1    NEW 
Molecular
reagents
All nucleic(18) cDNA(18)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000006622 (Evidence)
Ensembl Gene Model ENSMUSG00000028423 (Evidence)
Entrez Gene 74164 (Evidence)
DFCI TC1574373, TC1584146, TC1591467, TC1601724
DoTS DT.101330769, DT.101706598, DT.101737356, DT.97351549
NIA Mouse Gene Index U004205
EC 6.3.2.-
Consensus CDS Project CCDS18054.1, CCDS71359.1, CCDS71360.1
International Mouse Phenotyping Consortium Status Nfx1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006622 VEGA Gene Model | MGI Sequence Detail 55088 C57BL/6J ±  kb
transcript OTTMUST00000015100 VEGA | MGI Sequence Detail 4594 Not Applicable 
polypeptide OTTMUSP00000006983 VEGA | MGI Sequence Detail 1114 Not Applicable 

For the selected sequences
All sequences(70) RefSeq(12) UniProt(2)
Polymorphisms
RFLP(1) : SNPs within 2kb(213 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001374 R3H domain
InterPro IPR000967 Zinc finger, NF-X1-type
InterPro IPR019787 Zinc finger, PHD-finger
InterPro IPR019786 Zinc finger, PHD-type, conserved site
InterPro IPR001841 Zinc finger, RING-type
Protein Ontology PR:000011186 transcriptional repressor NF-X1
References
(Earliest) J:35463 Lopez-Fernandez LA, et al., Characterization of genes expressed early in mouse spermatogenesis, isolated from a subtractive cDNA library. Mamm Genome. 1996 Sep;7(9):698-700
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(42)
Other
accession IDs
MGI:1096567, MGI:1913784

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory