Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NEUROG2
  • Mouse genes Neurog2
  • Rat genes Neurog2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Neurog2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070888	E-box binding	Neurog2	IDA		Mouse	MGI:MGI:2686763|PMID:14697366
Molecular Function	GO:0005515	protein binding	NEUROG2	IPI	UniProtKB:Q99471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Neurog2	IPI	PR:Q9EQW6	Mouse	PMID:15655114
Molecular Function	GO:0043565	sequence-specific DNA binding	Neurog2	IDA		Mouse	PMID:17141158
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	NEUROG2	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	Neurog2	IDA		Mouse	PMID:19409883
Biological Process	GO:0007411	axon guidance	Neurog2	IMP	MGI:MGI:2159010	Mouse	PMID:12895419
Biological Process	GO:0007411	axon guidance	Neurog2	IMP	MGI:MGI:2159010	Mouse	PMID:15328020
Biological Process	GO:0021870	Cajal-Retzius cell differentiation	Neurog2	IDA		Mouse	PMID:18579678
Biological Process	GO:0045165	cell fate commitment	Neurog2	IGI	MGI:MGI:107754	Mouse	PMID:15229646
Biological Process	GO:0048469	cell maturation	Neurog2	IMP	MGI:MGI:2673381	Mouse	PMID:16766700
Biological Process	GO:0021954	central nervous system neuron development	Neurog2	IMP	MGI:MGI:2673381	Mouse	PMID:16410412
Biological Process	GO:0021954	central nervous system neuron development	Neurog2	IGI	MGI:MGI:96919	Mouse	PMID:16410412
Biological Process	GO:0021954	central nervous system neuron development	Neurog2	IMP	MGI:MGI:2159010	Mouse	PMID:16410412
Biological Process	GO:0021954	central nervous system neuron development	Neurog2	IMP	MGI:MGI:2159011	Mouse	PMID:16410412
Biological Process	GO:0071542	dopaminergic neuron differentiation	Neurog2	IMP	MGI:MGI:2673381	Mouse	PMID:16396906
Biological Process	GO:0030900	forebrain development	Neurog2	IMP	MGI:MGI:2159010	Mouse	PMID:15328020
Biological Process	GO:0022008	neurogenesis	Neurog2	IDA		Mouse	PMID:19050759
Biological Process	GO:0030182	neuron differentiation	Neurog2	IDA		Mouse	PMID:18579678
Biological Process	GO:0001764	neuron migration	Neurog2	IMP	MGI:MGI:2673381	Mouse	PMID:16396906
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	Neurog2	IDA		Mouse	MGI:MGI:2686763|PMID:14697366
Biological Process	GO:0045666	positive regulation of neuron differentiation	Neurog2	IDA		Mouse	PMID:18579678
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Neurog2	IDA		Mouse	PMID:23434913
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Neurog2	IGI	MGI:MGI:1926387	Mouse	PMID:16648472
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Neurog2	IMP	MGI:MGI:2159010	Mouse	PMID:16410412
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Neurog2	IMP	MGI:MGI:2673381	Mouse	PMID:16410412
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Neurog2	IDA		Mouse	PMID:15655114
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Neurog2	IGI	MGI:MGI:98510	Mouse	PMID:16648472
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Neurog2	IMP	MGI:MGI:2159011	Mouse	PMID:16410412

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern