Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NEU4
  • Mouse genes Neu4
  • Rat genes Neu4
  • Zfish genes neu4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Neu4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	NEU4	IDA		Human	PMID:15847605
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	Neu4	IDA		Mouse	MGI:MGI:4361102|PMID:19506080
Molecular Function	GO:0052796	exo-alpha-(2->8)-sialidase activity	NEU4	IDA		Human	PMID:15847605
Molecular Function	GO:0052796	exo-alpha-(2->8)-sialidase activity	Neu4	IDA		Mouse	MGI:MGI:5427293|PMID:22393058
Molecular Function	GO:0052796	exo-alpha-(2->8)-sialidase activity	Neu4	IDA		Mouse	MGI:MGI:4361102|PMID:19506080
Molecular Function	GO:0004308	exo-alpha-sialidase activity	NEU4	IDA		Human	PMID:14962670
Molecular Function	GO:0004308	exo-alpha-sialidase activity	NEU4	IDA		Human	PMID:15213228
Molecular Function	GO:0004308	exo-alpha-sialidase activity	Neu4	IDA		Mouse	PMID:14637003
Molecular Function	GO:0004308	exo-alpha-sialidase activity	neu4	IDA		Zfish	PMID:17708749
Molecular Function	GO:0005515	protein binding	NEU4	IPI	UniProtKB:O15162	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	NEU4	IPI	UniProtKB:Q99750	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	NEU4	IPI	UniProtKB:Q99750	Human	PMID:19447967
Molecular Function	GO:0005515	protein binding	NEU4	IPI	UniProtKB:Q99750	Human	PMID:21516116
Cellular Component	GO:0005783	endoplasmic reticulum	neu4	IDA		Zfish	PMID:17708749
Cellular Component	GO:0005764	lysosome	NEU4	IDA		Human	PMID:15213228
Cellular Component	GO:0005739	mitochondrion	Neu4	HDA		Mouse	PMID:18614015
Cellular Component	GO:0043005	neuron projection	Neu4	IDA		Mouse	MGI:MGI:5427293|PMID:22393058
Cellular Component	GO:0019866	organelle inner membrane	NEU4	IDA		Human	PMID:14962670
Cellular Component	GO:0005886	plasma membrane	Neu4	IDA		Mouse	MGI:MGI:5427293|PMID:22393058
Biological Process	GO:0006689	ganglioside catabolic process	NEU4	IDA		Human	PMID:15213228
Biological Process	GO:0006689	ganglioside catabolic process	NEU4	IDA		Human	PMID:15847605
Biological Process	GO:0006689	ganglioside catabolic process	Neu4	IDA		Mouse	MGI:MGI:4361102|PMID:19506080
Biological Process	GO:0001573	ganglioside metabolic process	neu4	IDA		Zfish	PMID:17708749
Biological Process	GO:0006516	glycoprotein catabolic process	NEU4	IDA		Human	PMID:15213228
Biological Process	GO:0006516	glycoprotein catabolic process	NEU4	IDA		Human	PMID:15847605
Biological Process	GO:0006516	glycoprotein catabolic process	Neu4	IDA		Mouse	MGI:MGI:5427293|PMID:22393058
Biological Process	GO:0006516	glycoprotein catabolic process	Neu4	IDA		Mouse	MGI:MGI:4361102|PMID:19506080
Biological Process	GO:0010977	negative regulation of neuron projection development	Neu4	IDA		Mouse	MGI:MGI:5427293|PMID:22393058
Biological Process	GO:0009313	oligosaccharide catabolic process	NEU4	IDA		Human	PMID:15213228

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern