Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NELFB
  • Mouse genes Nelfb
  • Rat genes Nelfb
  • Zfish genes nelfb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nelfb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NELFB	IPI	UniProtKB:P38398	Human	PMID:11739404
Molecular Function	GO:0005515	protein binding	NELFB	IPI	UniProtKB:P18615	Human	PMID:12612062
Molecular Function	GO:0005515	protein binding	NELFB	IPI	UniProtKB:P18615	Human	PMID:14667819
Molecular Function	GO:0005515	protein binding	NELFB	IPI	UniProtKB:P06241	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	NELFB	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	NELFB	IPI	UniProtKB:P27986	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	NELFB	IPI	UniProtKB:P62993	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	NELFB	IPI	UniProtKB:O43583	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	NELFB	IPI	UniProtKB:O75525	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	NELFB	IPI	UniProtKB:P10620	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	NELFB	IPI	UniProtKB:P38646	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	NELFB	IPI	UniProtKB:P18615	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	NELFB	IPI	UniProtKB:P18615	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	NELFB	IPI	UniProtKB:P18615	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	NELFB	IPI	UniProtKB:P18615	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Nelfb	IPI	UniProtKB:P19426|UniProtKB:Q8BG30|UniProtKB:Q922L6	Mouse	MGI:MGI:6250769|PMID:26010750
Cellular Component	GO:0005737	cytoplasm	NELFB	IDA		Human	GO_REF:0000054
Cellular Component	GO:0032021	NELF complex	NELFB	IPI		Human	PMID:12612062
Cellular Component	GO:0032021	NELF complex	NELFB	IDA		Human	PMID:12612062
Cellular Component	GO:0005634	nucleus	NELFB	IDA		Human	PMID:12612062
Biological Process	GO:0008283	cell population proliferation	Nelfb	IMP		Mouse	MGI:MGI:6270977|PMID:25773599
Biological Process	GO:2000737	negative regulation of stem cell differentiation	Nelfb	IMP		Mouse	MGI:MGI:3845453|PMID:19340312
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	NELFB	IDA		Human	PMID:12612062
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	Nelfb	IMP		Mouse	MGI:MGI:5576446|PMID:24656816
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	Nelfb	IMP		Mouse	MGI:MGI:3845453|PMID:19340312
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	Nelfb	IMP		Mouse	MGI:MGI:6270977|PMID:25773599
Biological Process	GO:1901534	positive regulation of hematopoietic progenitor cell differentiation	nelfb	IMP	ZFIN:ZDB-MRPHLNO-170117-2	Zfish	PMID:27520065
Biological Process	GO:1902038	positive regulation of hematopoietic stem cell differentiation	nelfb	IMP	ZFIN:ZDB-MRPHLNO-170117-2	Zfish	PMID:27520065
Biological Process	GO:0048863	stem cell differentiation	Nelfb	IMP		Mouse	MGI:MGI:6270977|PMID:25773599

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern