Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GCOM1,MYZAP,POLR2M
  • Mouse genes Myzap
  • Rat genes Myzap
  • Zfish genes myzap
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myzap

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MYZAP	IPI	UniProtKB:P63167	Human	PMID:20412299
Molecular Function	GO:0005515	protein binding	Myzap	IPI	UniProtKB:E9Q557	Mouse	MGI:MGI:4947500|PMID:20093627
Cellular Component	GO:0030864	cortical actin cytoskeleton	Myzap	IDA		Mouse	MGI:MGI:4947500|PMID:20093627
Cellular Component	GO:0005856	cytoskeleton	Myzap	IDA		Rat	PMID:20093627|RGD:8553434
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	Myzap	IDA		Mouse	MGI:MGI:4947500|PMID:20093627
Cellular Component	GO:0031674	I band	Myzap	IDA		Mouse	MGI:MGI:4947500|PMID:20093627
Cellular Component	GO:0016020	membrane	Myzap	IDA		Rat	PMID:20093627|RGD:8553434
Cellular Component	GO:0005635	nuclear envelope	POLR2M	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005665	RNA polymerase II, core complex	POLR2M	IPI	UniProtKB:P19387,UniProtKB:P24928,UniProtKB:P30876	Human	PMID:30190596
Cellular Component	GO:0097550	transcription preinitiation complex	POLR2M	IDA		Human	PMID:22231121
Biological Process	GO:0060047	heart contraction	myzap	IMP	ZFIN:ZDB-MRPHLNO-100427-13	Zfish	PMID:20093627
Biological Process	GO:0035556	intracellular signal transduction	Myzap	IDA		Mouse	MGI:MGI:4947500|PMID:20093627

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern