Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYOC
  • Mouse genes Myoc
  • Rat genes Myoc
  • Zfish genes myoc
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myoc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001968	fibronectin binding	MYOC	IPI	UniProtKB:P02751	Human	PMID:11773026
Molecular Function	GO:0005109	frizzled binding	MYOC	IPI	UniProtKB:O75084	Human	PMID:19188438
Molecular Function	GO:0005109	frizzled binding	MYOC	IPI	UniProtKB:Q9ULW2	Human	PMID:19188438
Molecular Function	GO:0005109	frizzled binding	MYOC	IPI	UniProtKB:Q9UP38	Human	PMID:19188438
Molecular Function	GO:0032027	myosin light chain binding	MYOC	IPI	UniProtKB:P10916	Human	PMID:11773029
Molecular Function	GO:0005515	protein binding	MYOC	IPI	UniProtKB:P10916	Human	PMID:11773029
Molecular Function	GO:0005515	protein binding	MYOC	IPI	UniProtKB:Q96PB7	Human	PMID:12019210
Molecular Function	GO:0005515	protein binding	MYOC	IPI	UniProtKB:D9ZGF6	Human	PMID:19188438
Molecular Function	GO:0005515	protein binding	MYOC	IPI	UniProtKB:Q9Y5W5	Human	PMID:19188438
Molecular Function	GO:0005515	protein binding	MYOC	IPI	UniProtKB:P09486	Human	PMID:20926826
Molecular Function	GO:0005515	protein binding	MYOC	IPI	UniProtKB:Q14515	Human	PMID:20926826
Molecular Function	GO:0005515	protein binding	MYOC	IPI	UniProtKB:O94856	Human	PMID:23897819
Molecular Function	GO:0005515	protein binding	MYOC	IPI	UniProtKB:Q8BMF8	Human	PMID:23897819
Molecular Function	GO:0005515	protein binding	MYOC	IPI	UniProtKB:Q92823	Human	PMID:23897819
Molecular Function	GO:0005515	protein binding	MYOC	IPI	UniProtKB:O43765	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Myoc	IPI	UniProtKB:Q810U3|UniProtKB:Q810U4|UniProtKB:Q8BMF8	Mouse	MGI:MGI:5527213|PMID:23897819
Molecular Function	GO:0005515	protein binding	Myoc	IPI	UniProtKB:Q61234	Mouse	MGI:MGI:5320812|PMID:22371502
Molecular Function	GO:0005515	protein binding	Myoc	IPI	UniProtKB:P97401|UniProtKB:Q8C4U3	Mouse	MGI:MGI:3842073|PMID:19188438
Molecular Function	GO:0005515	protein binding	Myoc	IPI	UniProtKB:Q9Z0F7	Mouse	MGI:MGI:5554368|PMID:16392033
Molecular Function	GO:0005515	protein binding	Myoc	IPI	PR:P63056	Mouse	PMID:12019210
Molecular Function	GO:0030971	receptor tyrosine kinase binding	Myoc	IPI	UniProtKB:P70424|UniProtKB:Q61526	Mouse	MGI:MGI:5527213|PMID:23897819
Cellular Component	GO:0062023	collagen-containing extracellular matrix	MYOC	IDA		Human	PMID:11773026
Cellular Component	GO:0005737	cytoplasm	Myoc	IDA		Rat	PMID:15610237|RGD:7401266
Cellular Component	GO:0031410	cytoplasmic vesicle	MYOC	IDA		Human	PMID:11431441
Cellular Component	GO:0005783	endoplasmic reticulum	Myoc	IDA		Mouse	MGI:MGI:5503270|PMID:23629661
Cellular Component	GO:0070062	extracellular exosome	MYOC	HDA		Human	PMID:21362503
Cellular Component	GO:0070062	extracellular exosome	MYOC	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	MYOC	IDA		Human	PMID:17317787
Cellular Component	GO:0005615	extracellular space	Myoc	IDA		Mouse	MGI:MGI:5554368|PMID:16392033
Cellular Component	GO:0005615	extracellular space	Myoc	IDA		Mouse	PMID:12019210
Cellular Component	GO:0005794	Golgi apparatus	MYOC	IDA		Human	PMID:11053284
Cellular Component	GO:0005794	Golgi apparatus	Myoc	IDA		Mouse	MGI:MGI:5503270|PMID:23629661
Cellular Component	GO:0097453	mesaxon	Myoc	IDA		Rat	PMID:12838505|RGD:1600847
Cellular Component	GO:0005743	mitochondrial inner membrane	MYOC	IDA		Human	PMID:17516541
Cellular Component	GO:0005758	mitochondrial intermembrane space	MYOC	IDA		Human	PMID:17516541
Cellular Component	GO:0005741	mitochondrial outer membrane	MYOC	IDA		Human	PMID:17516541
Cellular Component	GO:0035748	myelin sheath abaxonal region	Myoc	IDA		Rat	PMID:12838505|RGD:1600847
Cellular Component	GO:0033268	node of Ranvier	Myoc	IDA		Mouse	MGI:MGI:5527213|PMID:23897819
Cellular Component	GO:0043220	Schmidt-Lanterman incisure	Myoc	IDA		Rat	PMID:12838505|RGD:1600847
Biological Process	GO:0060348	bone development	Myoc	IDA		Mouse	MGI:MGI:5503270|PMID:23629661
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Myoc	IEP		Rat	PMID:17663725|RGD:7401258
Biological Process	GO:0045162	clustering of voltage-gated sodium channels	Myoc	IMP		Mouse	MGI:MGI:5527213|PMID:23897819
Biological Process	GO:0038133	ERBB2-ERBB3 signaling pathway	Myoc	IDA		Mouse	MGI:MGI:5527213|PMID:23897819
Biological Process	GO:0030237	female sex determination	myoc	IMP	ZFIN:ZDB-GENO-220511-1	Zfish	PMID:33573230
Biological Process	GO:0022011	myelination in peripheral nervous system	Myoc	IMP		Mouse	MGI:MGI:5527213|PMID:23897819
Biological Process	GO:0001953	negative regulation of cell-matrix adhesion	MYOC	IDA		Human	PMID:17984096
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	MYOC	IDA		Human	PMID:17984096
Biological Process	GO:0051497	negative regulation of stress fiber assembly	MYOC	IDA		Human	PMID:17984096
Biological Process	GO:0021675	nerve development	Myoc	IEP		Rat	PMID:12838505|RGD:1600847
Biological Process	GO:0031175	neuron projection development	MYOC	IMP		Human	PMID:19959812
Biological Process	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade	MYOC	IMP		Human	PMID:19188438
Biological Process	GO:0001649	osteoblast differentiation	MYOC	IDA		Human	PMID:23629661
Biological Process	GO:0001649	osteoblast differentiation	Myoc	IDA		Mouse	MGI:MGI:5503270|PMID:23629661
Biological Process	GO:0030335	positive regulation of cell migration	MYOC	IDA		Human	PMID:21656515
Biological Process	GO:0051894	positive regulation of focal adhesion assembly	MYOC	IDA		Human	PMID:18855004
Biological Process	GO:0051901	positive regulation of mitochondrial depolarization	MYOC	IDA		Human	PMID:17516541
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	MYOC	IDA		Human	PMID:21656515
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	MYOC	IDA		Human	PMID:21656515
Biological Process	GO:0051496	positive regulation of stress fiber assembly	MYOC	IDA		Human	PMID:19188438
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	MYOC	IDA		Human	PMID:18855004
Biological Process	GO:0043408	regulation of MAPK cascade	MYOC	IDA		Human	PMID:23629661
Biological Process	GO:0014734	skeletal muscle hypertrophy	Myoc	IDA		Mouse	MGI:MGI:5320812|PMID:22371502

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern