Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYO1E
  • Mouse genes Myo1e
  • Rat genes Myo1e
  • Zfish genes myo1ea
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myo1e

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	MYO1E	IDA		Human	PMID:11940582
Molecular Function	GO:0016887	ATP hydrolysis activity	MYO1E	IDA		Human	PMID:11940582
Molecular Function	GO:0005516	calmodulin binding	MYO1E	IDA		Human	PMID:11940582
Molecular Function	GO:0035091	phosphatidylinositol binding	MYO1E	IDA		Human	PMID:20860408
Molecular Function	GO:0005515	protein binding	MYO1E	IPI	UniProtKB:P21575	Human	PMID:17257598
Molecular Function	GO:0005515	protein binding	MYO1E	IPI	UniProtKB:P50570	Human	PMID:17257598
Molecular Function	GO:0005515	protein binding	MYO1E	IPI	UniProtKB:Q62910	Human	PMID:17257598
Molecular Function	GO:0005515	protein binding	MYO1E	IPI	UniProtKB:Q5VZK9	Human	PMID:19846667
Molecular Function	GO:0005515	protein binding	MYO1E	IPI	UniProtKB:Q8N8R7	Human	PMID:21458045
Molecular Function	GO:0044877	protein-containing complex binding	Myo1e	IDA		Rat	PMID:17257598|RGD:2312449
Cellular Component	GO:0005912	adherens junction	Myo1e	IDA		Mouse	MGI:MGI:4441423|PMID:19005011
Cellular Component	GO:0005903	brush border	Myo1e	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Cellular Component	GO:0005903	brush border	Myo1e	IDA		Mouse	MGI:MGI:5607232|PMID:20089841
Cellular Component	GO:0045334	clathrin-coated endocytic vesicle	MYO1E	IDA		Human	PMID:17257598
Cellular Component	GO:0032437	cuticular plate	Myo1e	IDA		Rat	PMID:12486594|RGD:1298992
Cellular Component	GO:0005737	cytoplasm	Myo1e	IDA		Mouse	MGI:MGI:4441423|PMID:19005011
Cellular Component	GO:0005856	cytoskeleton	MYO1E	IDA		Human	PMID:17257598
Cellular Component	GO:0070062	extracellular exosome	MYO1E	HDA		Human	PMID:20458337
Cellular Component	GO:0032991	protein-containing complex	Myo1e	IDA		Rat	PMID:17257598|RGD:2312449
Biological Process	GO:0006897	endocytosis	MYO1E	IMP		Human	PMID:17257598
Biological Process	GO:0032836	glomerular basement membrane development	Myo1e	IMP		Mouse	MGI:MGI:4441423|PMID:19005011
Biological Process	GO:0003094	glomerular filtration	Myo1e	IMP		Mouse	MGI:MGI:4441423|PMID:19005011
Biological Process	GO:0003094	glomerular filtration	myo1ea	IGI	ZFIN:ZDB-MRPHLNO-131014-2,ZFIN:ZDB-MRPHLNO-131014-3	Zfish	PMID:23977349
Biological Process	GO:0032835	glomerulus development	myo1ea	IGI	ZFIN:ZDB-MRPHLNO-131014-2,ZFIN:ZDB-MRPHLNO-131014-3	Zfish	PMID:23977349
Biological Process	GO:0030097	hemopoiesis	Myo1e	IMP	MGI:MGI:3526864	Mouse	PMID:17143286
Biological Process	GO:0001701	in utero embryonic development	Myo1e	IMP	MGI:MGI:3526864	Mouse	PMID:17143286
Biological Process	GO:0001822	kidney development	Myo1e	IMP	MGI:MGI:3526864	Mouse	PMID:17143286
Biological Process	GO:0006807	nitrogen compound metabolic process	Myo1e	IMP	MGI:MGI:3526864	Mouse	PMID:17143286
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	Myo1e	IMP	MGI:MGI:3526864	Mouse	PMID:17143286
Biological Process	GO:0072015	podocyte development	Myo1e	IMP		Mouse	MGI:MGI:4441423|PMID:19005011
Biological Process	GO:0035166	post-embryonic hemopoiesis	Myo1e	IMP	MGI:MGI:3526864	Mouse	PMID:17143286
Biological Process	GO:0001570	vasculogenesis	Myo1e	IMP	MGI:MGI:3526864	Mouse	PMID:17143286

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern