Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYO18A
  • Mouse genes Myo18a
  • Rat genes Myo18a
  • Zfish genes myo18aa,myo18ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Myo18a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	MYO18A	IDA		Human	PMID:23990465
Molecular Function	GO:0043531	ADP binding	MYO18A	IDA		Human	PMID:23990465
Molecular Function	GO:0005524	ATP binding	MYO18A	IDA		Human	PMID:23990465
Molecular Function	GO:0005515	protein binding	MYO18A	IPI	UniProtKB:Q9H4A6	Human	PMID:19837035
Molecular Function	GO:0005515	protein binding	MYO18A	IPI	UniProtKB:Q9H4A6	Human	PMID:24485452
Molecular Function	GO:0005515	protein binding	MYO18A	IPI	UniProtKB:P08571	Human	PMID:25965346
Molecular Function	GO:0005515	protein binding	MYO18A	IPI	UniProtKB:P21127	Human	PMID:25965346
Molecular Function	GO:0005515	protein binding	MYO18A	IPI	UniProtKB:P21757	Human	PMID:25965346
Molecular Function	GO:0003723	RNA binding	MYO18A	HDA		Human	PMID:22681889
Cellular Component	GO:0042641	actomyosin	MYO18A	IDA		Human	PMID:18854160
Cellular Component	GO:0005903	brush border	Myo18a	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Cellular Component	GO:0005856	cytoskeleton	Myo18a	IDA		Mouse	PMID:10733906
Cellular Component	GO:0016020	membrane	MYO18A	HDA		Human	PMID:19946888
Cellular Component	GO:0045335	phagocytic vesicle	Myo18a	IDA		Mouse	PMID:19144319
Cellular Component	GO:0005802	trans-Golgi network	MYO18A	IDA		Human	PMID:19837035
Biological Process	GO:0031032	actomyosin structure organization	MYO18A	IMP		Human	PMID:18854160
Biological Process	GO:0090164	asymmetric Golgi ribbon formation	MYO18A	IMP		Human	PMID:19837035
Biological Process	GO:0016477	cell migration	MYO18A	IMP		Human	PMID:18854160
Biological Process	GO:0007160	cell-matrix adhesion	myo18ab	IGI	ZFIN:ZDB-GENE-080425-5	Zfish	PMID:27824130
Biological Process	GO:0007160	cell-matrix adhesion	myo18aa	IGI	ZFIN:ZDB-GENE-080423-1	Zfish	PMID:27824130
Biological Process	GO:0071346	cellular response to type II interferon	Myo18a	IDA		Mouse	PMID:19144319
Biological Process	GO:0007030	Golgi organization	MYO18A	IMP		Human	PMID:19837035
Biological Process	GO:0007030	Golgi organization	myo18ab	IGI	ZFIN:ZDB-GENE-080425-5	Zfish	PMID:27824130
Biological Process	GO:0007030	Golgi organization	myo18aa	IGI	ZFIN:ZDB-GENE-080423-1	Zfish	PMID:27824130
Biological Process	GO:0090161	Golgi ribbon formation	MYO18A	IMP		Human	PMID:19837035
Biological Process	GO:0048194	Golgi vesicle budding	MYO18A	IMP		Human	PMID:19837035
Biological Process	GO:0060415	muscle tissue morphogenesis	myo18ab	IMP	ZFIN:ZDB-MRPHLNO-151217-3	Zfish	PMID:27824130
Biological Process	GO:0060415	muscle tissue morphogenesis	myo18ab	IGI	ZFIN:ZDB-GENE-010724-1	Zfish	PMID:27824130
Biological Process	GO:0060415	muscle tissue morphogenesis	myo18ab	IGI	ZFIN:ZDB-GENE-060531-28	Zfish	PMID:27824130
Biological Process	GO:0060415	muscle tissue morphogenesis	myo18ab	IGI	ZFIN:ZDB-GENE-070928-35	Zfish	PMID:27824130
Biological Process	GO:0043066	negative regulation of apoptotic process	MYO18A	IMP		Human	PMID:24485452
Biological Process	GO:1903028	positive regulation of opsonization	MYO18A	IMP		Human	PMID:21123169
Biological Process	GO:1903028	positive regulation of opsonization	Myo18a	IMP		Mouse	MGI:MGI:5810257|PMID:21123169
Biological Process	GO:0050714	positive regulation of protein secretion	MYO18A	IMP		Human	PMID:23345592
Biological Process	GO:0043030	regulation of macrophage activation	MYO18A	IMP		Human	PMID:25965346
Biological Process	GO:0043030	regulation of macrophage activation	Myo18a	IMP		Mouse	MGI:MGI:5810252|PMID:25965346
Biological Process	GO:0048741	skeletal muscle fiber development	myo18ab	IMP	ZFIN:ZDB-MRPHLNO-151217-3	Zfish	PMID:25160974
Biological Process	GO:0048741	skeletal muscle fiber development	myo18ab	IMP	ZFIN:ZDB-TALEN-151217-2	Zfish	PMID:25160974
Biological Process	GO:0048741	skeletal muscle fiber development	myo18ab	IGI	ZFIN:ZDB-MRPHLNO-151217-2,ZFIN:ZDB-MRPHLNO-151217-3	Zfish	PMID:25160974
Biological Process	GO:0048741	skeletal muscle fiber development	myo18aa	IMP	ZFIN:ZDB-TALEN-151217-1	Zfish	PMID:25160974
Biological Process	GO:0048741	skeletal muscle fiber development	myo18aa	IMP	ZFIN:ZDB-MRPHLNO-151217-2	Zfish	PMID:25160974
Biological Process	GO:0048741	skeletal muscle fiber development	myo18aa	IGI	ZFIN:ZDB-MRPHLNO-151217-2,ZFIN:ZDB-MRPHLNO-151217-3	Zfish	PMID:25160974
Biological Process	GO:0014866	skeletal myofibril assembly	myo18ab	IMP	ZFIN:ZDB-MRPHLNO-151217-3	Zfish	PMID:25160974
Biological Process	GO:0014866	skeletal myofibril assembly	myo18aa	IMP	ZFIN:ZDB-MRPHLNO-151217-2	Zfish	PMID:25160974

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern