Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYLK3
  • Mouse genes Mylk3
  • Rat genes Mylk3
  • Zfish genes mylk3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mylk3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004683	calmodulin-dependent protein kinase activity	Mylk3	IDA		Mouse	MGI:MGI:3763863|PMID:17885681
Molecular Function	GO:0004683	calmodulin-dependent protein kinase activity	Mylk3	IDA		Rat	PMID:17885681|RGD:8554371
Molecular Function	GO:0004687	myosin light chain kinase activity	Mylk3	IDA		Mouse	MGI:MGI:3763863|PMID:17885681
Molecular Function	GO:0004687	myosin light chain kinase activity	Mylk3	IDA		Mouse	MGI:MGI:3841874|PMID:18202317
Molecular Function	GO:0004687	myosin light chain kinase activity	Mylk3	IMP		Rat	PMID:18202317|RGD:8554765
Cellular Component	GO:0015629	actin cytoskeleton	Mylk3	IDA		Mouse	MGI:MGI:3841874|PMID:18202317
Cellular Component	GO:0005737	cytoplasm	Mylk3	IDA		Mouse	MGI:MGI:3841874|PMID:18202317
Cellular Component	GO:0005829	cytosol	Mylk3	IDA		Rat	PMID:17885681|RGD:8554371
Biological Process	GO:0055003	cardiac myofibril assembly	Mylk3	IMP		Rat	PMID:17885681|RGD:8554371
Biological Process	GO:0071347	cellular response to interleukin-1	MYLK3	IMP		Human	PMID:18390750
Biological Process	GO:0003007	heart morphogenesis	mylk3	IMP	ZFIN:ZDB-MRPHLNO-080108-3	Zfish	PMID:17885681
Biological Process	GO:0003007	heart morphogenesis	mylk3	IMP	ZFIN:ZDB-MRPHLNO-080108-4	Zfish	PMID:17885681
Biological Process	GO:0003007	heart morphogenesis	mylk3	IMP	ZFIN:ZDB-MRPHLNO-080108-6	Zfish	PMID:17885681
Biological Process	GO:0060298	positive regulation of sarcomere organization	Mylk3	IDA		Rat	PMID:17885681|RGD:8554371
Biological Process	GO:0006468	protein phosphorylation	Mylk3	IDA		Mouse	MGI:MGI:3763863|PMID:17885681
Biological Process	GO:0006468	protein phosphorylation	Mylk3	IDA		Rat	PMID:17885681|RGD:8554371
Biological Process	GO:0002528	regulation of vascular permeability involved in acute inflammatory response	MYLK3	IMP		Human	PMID:18390750
Biological Process	GO:0045214	sarcomere organization	Mylk3	IDA		Mouse	MGI:MGI:3841874|PMID:18202317
Biological Process	GO:0045214	sarcomere organization	Mylk3	IMP		Rat	PMID:18202317|RGD:8554765
Biological Process	GO:0048769	sarcomerogenesis	Mylk3	IMP		Rat	PMID:17885681|RGD:8554371
Biological Process	GO:0048769	sarcomerogenesis	mylk3	IMP		Zfish	PMID:17885681|ZFIN:ZDB-PUB-070924-8
Biological Process	GO:0048769	sarcomerogenesis	mylk3	IMP	ZFIN:ZDB-MRPHLNO-080108-3	Zfish	PMID:17885681
Biological Process	GO:0055005	ventricular cardiac myofibril assembly	mylk3	IMP		Zfish	PMID:17885681|ZFIN:ZDB-PUB-070924-8

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern