Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MYLIP
  • Mouse genes Mylip
  • Rat genes Mylip
  • Zfish genes mylipa,mylipb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mylip

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008092	cytoskeletal protein binding	MYLIP	IDA		Human	PMID:10593918
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q9Y2B0	Human	PMID:12826659
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q8N448	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q8TD10	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q8WWW0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q9Y3Q8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q8N448	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q8N448	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q8WWW0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:B2RXF5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:P0CG21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:P55771	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q03989	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q05516	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q5JST6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q5T7N3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q6NSM0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q6UY14-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q7Z4V0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q86UR1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q86WV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q8N8B7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q8TAU3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q96ED9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q96IK5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q99592	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q9BWG6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q9C086	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q9NQT4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q9NTX9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:D3DTS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:G5E9A7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:O43464	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:P54252	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q86WV8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q92870-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MYLIP	IPI	UniProtKB:Q9UMF0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	mylipa	IPI	UniProtKB:A9JTC0	Zfish	PMID:14651927|ZFIN:ZDB-PUB-031204-3
Molecular Function	GO:0005515	protein binding	mylipa	IPI	UniProtKB:P48036	Zfish	PMID:14651927|ZFIN:ZDB-PUB-031204-3
Molecular Function	GO:0061630	ubiquitin protein ligase activity	MYLIP	IDA		Human	PMID:21685362
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Mylip	IMP		Mouse	PMID:19520913
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	MYLIP	IDA		Human	PMID:14550572
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Mylip	IMP		Mouse	MGI:MGI:3849777|PMID:19520913
Cellular Component	GO:0005737	cytoplasm	mylipa	IDA		Zfish	PMID:14651927
Biological Process	GO:0042632	cholesterol homeostasis	Mylip	IMP		Mouse	MGI:MGI:3849777|PMID:19520913
Biological Process	GO:0007369	gastrulation	mylipa	IMP		Zfish	PMID:18248225|ZFIN:ZDB-PUB-050628-2
Biological Process	GO:0007369	gastrulation	mylipa	IMP		Zfish	PMID:14651927
Biological Process	GO:0010989	negative regulation of low-density lipoprotein particle clearance	Mylip	IDA		Mouse	MGI:MGI:3849777|PMID:19520913
Biological Process	GO:0010977	negative regulation of neuron projection development	MYLIP	IMP		Human	PMID:10593918
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	mylipa	IGI	ZFIN:ZDB-GENE-990415-223	Zfish	PMID:18248225|ZFIN:ZDB-PUB-050628-2
Biological Process	GO:0007399	nervous system development	MYLIP	IMP		Human	PMID:10593918
Biological Process	GO:0045732	positive regulation of protein catabolic process	Mylip	IDA		Mouse	MGI:MGI:3849777|PMID:19520913
Biological Process	GO:0031648	protein destabilization	Mylip	IDA		Mouse	MGI:MGI:3849777|PMID:19520913
Biological Process	GO:0016567	protein ubiquitination	MYLIP	IDA		Human	PMID:14550572
Biological Process	GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process	Mylip	IMP		Mouse	MGI:MGI:3849777|PMID:19520913
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Mylip	IDA		Mouse	MGI:MGI:3849777|PMID:19520913

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern