Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MXI1
  • Mouse genes Mxi1
  • Rat genes Mxi1
  • Zfish genes mxi1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mxi1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	MXI1	IDA		Human	PMID:11875718
Molecular Function	GO:0005515	protein binding	MXI1	IPI	UniProtKB:P61244	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	MXI1	IPI	UniProtKB:O75356	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MXI1	IPI	UniProtKB:P61244	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MXI1	IPI	UniProtKB:P61244-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MXI1	IPI	UniProtKB:Q13137	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MXI1	IPI	UniProtKB:Q53RC5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MXI1	IPI	UniProtKB:P61244	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	MXI1	IPI	UniProtKB:P61244	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	Mxi1	IPI	UniProtKB:Q60520	Mouse	MGI:MGI:79478|PMID:8649810
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	MXI1	IDA		Human	PMID:8425219
Cellular Component	GO:0005737	cytoplasm	Mxi1	IDA		Rat	PMID:9130602|RGD:1599896
Cellular Component	GO:0005829	cytosol	MXI1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	MXI1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MXI1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Mxi1	IDA		Mouse	PMID:15467743
Cellular Component	GO:0005634	nucleus	Mxi1	IDA		Rat	PMID:11498788|RGD:70302
Cellular Component	GO:0005634	nucleus	Mxi1	IDA		Rat	PMID:9130602|RGD:1599896
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	MXI1	IDA		Human	PMID:8425219
Biological Process	GO:0001825	blastocyst formation	Mxi1	IMP		Mouse	PMID:27869233
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	MXI1	IDA		Human	PMID:11875718
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Mxi1	IDA		Mouse	PMID:15467743
Biological Process	GO:0006355	regulation of DNA-templated transcription	Mxi1	IDA		Rat	PMID:11498788|RGD:70302

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern