Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MUC5B
  • Mouse genes Muc5b
  • Rat genes Muc5b
  • Zfish genes muc5.1,muc5.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Muc5b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MUC5B	IPI	UniProtKB:P47515	Human	PMID:12787366
Molecular Function	GO:0005515	protein binding	MUC5B	IPI	UniProtKB:P47516	Human	PMID:12787366
Molecular Function	GO:0005515	protein binding	MUC5B	IPI	UniProtKB:P47543	Human	PMID:12787366
Molecular Function	GO:0005515	protein binding	MUC5B	IPI	UniProtKB:P02808	Human	PMID:1718282
Cellular Component	GO:0070062	extracellular exosome	MUC5B	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	MUC5B	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	Muc5b	IDA		Mouse	PMID:23272068
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	MUC5B	IDA		Human	GO_REF:0000052
Biological Process	GO:0042742	defense response to bacterium	Muc5b	IMP	MGI:MGI:5576290	Mouse	PMID:24317696
Biological Process	GO:0043030	regulation of macrophage activation	Muc5b	IMP	MGI:MGI:5576290	Mouse	PMID:24317696

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern