Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MTA2
  • Mouse genes Mta2
  • Rat genes Mta2
  • Zfish genes mta2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mta2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004407	histone deacetylase activity	Mta2	IDA		Mouse	PMID:10444591
Molecular Function	GO:0042826	histone deacetylase binding	Mta2	IPI	RGD:1309799	Rat	PMID:18413351|RGD:10041067
Molecular Function	GO:0031492	nucleosomal DNA binding	MTA2	HDA		Human	PMID:16217013
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q9UKT9	Human	PMID:17646674
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q13547	Human	PMID:17956988
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q13547	Human	PMID:18451879
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q96KQ7	Human	PMID:18451879
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q13547	Human	PMID:19703393
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q16576	Human	PMID:19703393
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q13547	Human	PMID:20127688
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q99497	Human	PMID:20127688
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q13547	Human	PMID:21258344
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q13547	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q16576	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q17R98	Human	PMID:25150861
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:O60315	Human	PMID:26028330
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q96KQ7	Human	PMID:26028330
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q03468	Human	PMID:26030138
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q13547	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q13547	Human	PMID:26949739
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q16576	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q13547	Human	PMID:28179136
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q16576	Human	PMID:28179136
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q13547	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q16576	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q13547	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	MTA2	IPI	UniProtKB:Q16576	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	Mta2	IPI	UniProtKB:P20263|UniProtKB:Q61539|UniProtKB:Q8BX22	Mouse	MGI:MGI:5320277|PMID:20362541
Molecular Function	GO:0005515	protein binding	Mta2	IPI	UniProtKB:O09106|UniProtKB:P70288	Mouse	MGI:MGI:4454226|PMID:20404188
Molecular Function	GO:0005515	protein binding	Mta2	IPI	UniProtKB:P12813	Mouse	MGI:MGI:5644023|PMID:19321449
Molecular Function	GO:0005515	protein binding	Mta2	IPI	UniProtKB:O09106|UniProtKB:P70288	Mouse	MGI:MGI:3844744|PMID:19424149
Molecular Function	GO:0005515	protein binding	Mta2	IPI	UniProtKB:P23772	Mouse	MGI:MGI:4844227|PMID:20636338
Molecular Function	GO:0005515	protein binding	Mta2	IPI	UniProtKB:O09106|UniProtKB:P70288	Mouse	MGI:MGI:5548024|PMID:24240174
Molecular Function	GO:0005515	protein binding	Mta2	IPI	UniProtKB:Q8VI24	Mouse	MGI:MGI:5314844|PMID:22334647
Molecular Function	GO:0005515	protein binding	Mta2	IPI	UniProtKB:E9Q9M8	Mouse	MGI:MGI:6867105|PMID:34180153
Molecular Function	GO:0005515	protein binding	Mta2	IPI	UniProtKB:Q8VI24	Mouse	MGI:MGI:6280169|PMID:30726206
Molecular Function	GO:0005515	protein binding	Mta2	IPI	UniProtKB:P20263	Mouse	MGI:MGI:4943831|PMID:20362542
Molecular Function	GO:0005515	protein binding	Mta2	IPI	PR:Q60973	Mouse	PMID:11836251
Molecular Function	GO:0005515	protein binding	Mta2	IPI	PR:Q9R190	Mouse	PMID:11836251
Molecular Function	GO:0005515	protein binding	Mta2	IPI	PR:O35615-1	Mouse	PMID:19654328
Molecular Function	GO:0005515	protein binding	Mta2	IPI	PR:Q60972	Mouse	PMID:14645126
Molecular Function	GO:0005515	protein binding	Mta2	IPI	PR:Q9Z2D8	Mouse	PMID:16462733
Molecular Function	GO:0005515	protein binding	Mta2	IPI	PR:Q9ER74	Mouse	PMID:11836251
Molecular Function	GO:0005515	protein binding	Mta2	IPI	PR:O09106	Mouse	PMID:11836251
Molecular Function	GO:0005515	protein binding	Mta2	IPI	PR:O09106	Mouse	PMID:14645126
Molecular Function	GO:0005515	protein binding	Mta2	IPI	PR:P70288	Mouse	PMID:11836251
Molecular Function	GO:0005515	protein binding	Mta2	IPI	PR:Q60973	Mouse	PMID:14645126
Molecular Function	GO:0005515	protein binding	Mta2	IPI	PR:O09106	Mouse	PMID:16462733
Molecular Function	GO:0005515	protein binding	Mta2	IPI	PR:Q8K4B0	Mouse	PMID:11836251
Molecular Function	GO:0005515	protein binding	Mta2	IPI	PR:Q8K4B0	Mouse	PMID:16462733
Molecular Function	GO:0005515	protein binding	Mta2	IPI	RGD:1306021	Rat	PMID:18067919|RGD:2326010
Molecular Function	GO:0005515	protein binding	Mta2	IPI	RGD:620365	Rat	PMID:18413351|RGD:10041067
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	MTA2	IPI	UniProtKB:Q8IX07	Human	PMID:15920471
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	MTA2	IPI	UniProtKB:Q96BF6	Human	PMID:22926524
Molecular Function	GO:0003712	transcription coregulator activity	Mta2	IDA		Mouse	MGI:MGI:4844227|PMID:20636338
Cellular Component	GO:0000785	chromatin	MTA2	HDA		Human	PMID:16217013
Cellular Component	GO:0000781	chromosome, telomeric region	MTA2	IDA		Human	PMID:25150861
Cellular Component	GO:0000118	histone deacetylase complex	Mta2	IDA		Mouse	PMID:10444591
Cellular Component	GO:0016020	membrane	MTA2	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	MTA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MTA2	IDA		Human	PMID:28977666
Cellular Component	GO:0005634	nucleus	MTA2	IDA		Human	PMID:33283408
Cellular Component	GO:0005634	nucleus	Mta2	IDA		Mouse	PMID:16462733
Cellular Component	GO:0005634	nucleus	Mta2	IDA		Mouse	PMID:20720167
Cellular Component	GO:0005634	nucleus	Mta2	IDA		Mouse	PMID:11749719
Cellular Component	GO:0005634	nucleus	Mta2	IDA		Rat	PMID:18067919|RGD:2326010
Cellular Component	GO:0016581	NuRD complex	MTA2	IDA		Human	PMID:19644445
Cellular Component	GO:0016581	NuRD complex	MTA2	IDA		Human	PMID:22926524
Cellular Component	GO:0016581	NuRD complex	MTA2	IDA		Human	PMID:33283408
Cellular Component	GO:0016581	NuRD complex	Mta2	IPI	PR:O09106	Mouse	PMID:16462733
Cellular Component	GO:0016581	NuRD complex	Mta2	IDA		Mouse	PMID:14645126
Cellular Component	GO:0016581	NuRD complex	Mta2	IPI	PR:Q8K4B0	Mouse	PMID:16462733
Cellular Component	GO:0016581	NuRD complex	Mta2	IPI	PR:Q9Z2D8	Mouse	PMID:16462733
Cellular Component	GO:0032991	protein-containing complex	MTA2	HDA		Human	PMID:16217013
Cellular Component	GO:0005667	transcription regulator complex	MTA2	IDA		Human	PMID:15920471
Biological Process	GO:0006338	chromatin remodeling	MTA2	HDA		Human	PMID:16217013
Biological Process	GO:0006338	chromatin remodeling	MTA2	IDA		Human	PMID:9790534
Biological Process	GO:0006306	DNA methylation	Mta2	IMP		Mouse	PMID:20720167
Biological Process	GO:0031101	fin regeneration	mta2	IMP	ZFIN:ZDB-MRPHLNO-140930-7	Zfish	PMID:24779377
Biological Process	GO:0016575	histone deacetylation	MTA2	IDA		Human	PMID:10444591
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Mta2	IDA		Mouse	MGI:MGI:4844227|PMID:20636338
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Mta2	IDA		Mouse	PMID:11749719
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mta2	IDA		Mouse	PMID:11749719
Biological Process	GO:0010762	regulation of fibroblast migration	Mta2	IDA		Rat	PMID:24468085|RGD:9588228

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern