Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MRC1
  • Mouse genes Mrc1
  • Rat genes Mrc1
  • Zfish genes mrc1a,mrc1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mrc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0038024	cargo receptor activity	MRC1	IDA		Human	PMID:20035344
Molecular Function	GO:0005537	mannose binding	Mrc1	IDA		Mouse	PMID:1421407
Molecular Function	GO:0005515	protein binding	MRC1	IPI	UniProtKB:P9WK61	Human	PMID:11222859
Molecular Function	GO:0005515	protein binding	Mrc1	IPI	UniProtKB:P0DTC2	Mouse	MGI:MGI:6467710|PMID:32766577
Molecular Function	GO:0004888	transmembrane signaling receptor activity	Mrc1	IDA		Mouse	PMID:1421407
Cellular Component	GO:0009986	cell surface	Mrc1	IDA		Mouse	PMID:1421407
Cellular Component	GO:0010008	endosome membrane	MRC1	IDA		Human	PMID:20035344
Cellular Component	GO:0005886	plasma membrane	MRC1	IDA		Human	PMID:20035344
Biological Process	GO:0071353	cellular response to interleukin-4	Mrc1	IDA		Mouse	PMID:22832163
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Mrc1	IDA		Mouse	PMID:22832163
Biological Process	GO:0071346	cellular response to type II interferon	Mrc1	IDA		Mouse	PMID:22832163
Biological Process	GO:0006898	receptor-mediated endocytosis	MRC1	IDA		Human	PMID:20035344

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern