Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MRAP
  • Mouse genes Mrap
  • Rat genes Mrap
  • Zfish genes mrap
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mrap

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031780	corticotropin hormone receptor binding	MRAP	IPI	UniProtKB:Q01718	Human	PMID:19329486
Molecular Function	GO:0004978	corticotropin receptor activity	mrap	IDA		Zfish	PMID:20138960
Molecular Function	GO:0042802	identical protein binding	MRAP	IPI	UniProtKB:Q8TCY5	Human	PMID:18077336
Molecular Function	GO:0042802	identical protein binding	MRAP	IPI	UniProtKB:Q8TCY5	Human	PMID:20371771
Molecular Function	GO:0031779	melanocortin receptor binding	mrap	IPI	UniProtKB:A7Y4C2	Zfish	PMID:26752246
Molecular Function	GO:0017046	peptide hormone binding	mrap	IPI	UniProtKB:P01189	Zfish	PMID:26752246
Molecular Function	GO:0005515	protein binding	MRAP	IPI	UniProtKB:Q01718	Human	PMID:18077336
Molecular Function	GO:0005515	protein binding	MRAP	IPI	UniProtKB:P32245	Human	PMID:19329486
Molecular Function	GO:0005515	protein binding	MRAP	IPI	UniProtKB:P33032	Human	PMID:19329486
Molecular Function	GO:0005515	protein binding	MRAP	IPI	UniProtKB:P41968	Human	PMID:19329486
Molecular Function	GO:0005515	protein binding	MRAP	IPI	UniProtKB:Q01726	Human	PMID:19329486
Molecular Function	GO:0005515	protein binding	MRAP	IPI	UniProtKB:Q96G30	Human	PMID:19329486
Molecular Function	GO:0005515	protein binding	MRAP	IPI	UniProtKB:Q96G30	Human	PMID:20371771
Molecular Function	GO:0005515	protein binding	MRAP	IPI	UniProtKB:Q01718	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	MRAP	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MRAP	IPI	UniProtKB:P28329-3	Human	PMID:32814053
Molecular Function	GO:0070996	type 1 melanocortin receptor binding	MRAP	IPI	UniProtKB:Q01726	Human	PMID:19329486
Molecular Function	GO:0031781	type 3 melanocortin receptor binding	MRAP	IPI	UniProtKB:P41968	Human	PMID:19329486
Molecular Function	GO:0031782	type 4 melanocortin receptor binding	MRAP	IPI	UniProtKB:P32245	Human	PMID:19329486
Molecular Function	GO:0031783	type 5 melanocortin receptor binding	MRAP	IPI	UniProtKB:P33032	Human	PMID:19329486
Cellular Component	GO:0005783	endoplasmic reticulum	MRAP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	MRAP	IDA		Human	PMID:19329486
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	MRAP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	MRAP	IDA		Human	PMID:19329486
Cellular Component	GO:0005886	plasma membrane	mrap	IDA		Zfish	PMID:20138960
Biological Process	GO:0050873	brown fat cell differentiation	Mrap	IDA		Mouse	PMID:18492766
Biological Process	GO:0106072	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	MRAP	IDA		Human	PMID:19329486
Biological Process	GO:1903077	negative regulation of protein localization to plasma membrane	MRAP	IDA		Human	PMID:19329486
Biological Process	GO:0106071	positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	MRAP	IDA		Human	PMID:19329486
Biological Process	GO:0106071	positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	mrap	IDA		Zfish	PMID:20138960
Biological Process	GO:0034394	protein localization to cell surface	mrap	IDA		Zfish	PMID:20138960
Biological Process	GO:0072659	protein localization to plasma membrane	MRAP	IDA		Human	PMID:19329486

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern