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Mrap Gene Detail
Summary
  • Symbol
    Mrap
  • Name
    melanocortin 2 receptor accessory protein
  • Synonyms
    1110025G12Rik, C21ORF61
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924287
    NCBI Gene: 77037
Location & Maps
more
  • Sequence Map
    Chr16:90738324-90749785 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11462 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    MRAP, melanocortin 2 receptor accessory protein
  • Vertebrate Orthologs
    7
  • Human Ortholog
    MRAP, melanocortin 2 receptor accessory protein
    Orthology source: HGNC, HomoloGene
  • Synonyms
    B27, C21orf61, FALP, FGD2, GCCD2
  • Links
    NCBI Gene ID: 56246
    neXtProt AC: NX_Q8TCY5

  • Chr Location
    21q22.1; chr21:32291813-32314784 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human MRAP associations

Human Disease Mouse Models
       Glucocorticoid Deficiency 2; GCCD2   OMIM: 607398
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    7
  • Targeted
    7
  • Genomic Mutations
    7 involving Mrap
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019934 VEGA Gene Model | MGI Sequence Detail 11462 C57BL/6J ±  kb
transcript OTTMUST00000047509 VEGA | MGI Sequence Detail 1001 Not Applicable  
polypeptide OTTMUSP00000021491 VEGA | MGI Sequence Detail 127 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    109 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000010557 melanocortin-2 receptor accessory protein
  • InterPro Domains
    IPR028111 Melanocortin-2 receptor accessory protein family
Molecular
Reagents
less
  • All nucleic 33
    cDNA 33

    Microarray probesets 5
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory