Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MLF1
  • Mouse genes Mlf1
  • Rat genes Mlf1
  • Zfish genes mlf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mlf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Mlf1	IDA		Mouse	MGI:MGI:3696586|PMID:17008314
Molecular Function	GO:0005515	protein binding	MLF1	IPI	UniProtKB:P63104	Human	PMID:12176995
Molecular Function	GO:0005515	protein binding	MLF1	IPI	UniProtKB:Q9UNS2	Human	PMID:15861129
Molecular Function	GO:0005515	protein binding	MLF1	IPI	UniProtKB:P43364	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	MLF1	IPI	UniProtKB:O52302	Human	PMID:20374249
Molecular Function	GO:0005515	protein binding	MLF1	IPI	UniProtKB:P62258	Human	PMID:22151054
Molecular Function	GO:0005515	protein binding	MLF1	IPI	UniProtKB:O75190	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	MLF1	IPI	UniProtKB:O75190	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	MLF1	IPI	UniProtKB:Q13200	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	MLF1	IPI	UniProtKB:Q15773	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	MLF1	IPI	UniProtKB:Q9BTE6-2	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	MLF1	IPI	UniProtKB:P43364	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	MLF1	IPI	UniProtKB:Q9BTE6-2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MLF1	IPI	UniProtKB:P43364	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Mlf1	IPI	UniProtKB:Q00PI9	Mouse	MGI:MGI:3696586|PMID:17008314
Molecular Function	GO:0005515	protein binding	Mlf1	IPI	UniProtKB:Q99J45	Mouse	MGI:MGI:2388865|PMID:12176995
Molecular Function	GO:0005515	protein binding	Mlf1	IPI	UniProtKB:O35598|UniProtKB:P09405|UniProtKB:Q9CXW3	Mouse	MGI:MGI:2388865|PMID:12176995
Molecular Function	GO:0005515	protein binding	Mlf1	IPI	UniProtKB:P63101	Mouse	MGI:MGI:2388865|PMID:12176995
Molecular Function	GO:0005515	protein binding	Mlf1	IPI	UniProtKB:P63101	Mouse	MGI:MGI:3696586|PMID:17008314
Molecular Function	GO:0005515	protein binding	Mlf1	IPI	UniProtKB:P63168	Mouse	MGI:MGI:2388865|PMID:12176995
Molecular Function	GO:0005515	protein binding	Mlf1	IPI	UniProtKB:Q9Z1D1	Mouse	MGI:MGI:2388865|PMID:12176995
Molecular Function	GO:0005515	protein binding	Mlf1	IPI	PR:Q8C4M7	Mouse	PMID:15116101
Molecular Function	GO:0019904	protein domain specific binding	MLF1	IDA		Human	PMID:12176995
Cellular Component	GO:0036064	ciliary basal body	Mlf1	IDA		Mouse	MGI:MGI:5883143|PMID:27914912
Cellular Component	GO:0097546	ciliary base	Mlf1	IDA		Mouse	PMID:27914912
Cellular Component	GO:0005929	cilium	Mlf1	IDA		Mouse	MGI:MGI:5883143|PMID:27914912
Cellular Component	GO:0005737	cytoplasm	Mlf1	IDA		Mouse	MGI:MGI:2388865|PMID:12176995
Cellular Component	GO:0005737	cytoplasm	Mlf1	IDA		Mouse	PMID:25446099
Cellular Component	GO:0031514	motile cilium	Mlf1	IDA		Mouse	PMID:23300604
Cellular Component	GO:0097730	non-motile cilium	Mlf1	IDA		Mouse	PMID:23300604
Cellular Component	GO:0005634	nucleus	MLF1	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	Mlf1	IDA		Mouse	MGI:MGI:3696586|PMID:17008314
Cellular Component	GO:0048471	perinuclear region of cytoplasm	MLF1	IDA		Human	PMID:15861129
Biological Process	GO:0006351	DNA-templated transcription	Mlf1	IDA		Mouse	MGI:MGI:3696586|PMID:17008314
Biological Process	GO:0002318	myeloid progenitor cell differentiation	Mlf1	IDA		Mouse	MGI:MGI:1346932|PMID:10523300
Biological Process	GO:1902806	regulation of cell cycle G1/S phase transition	MLF1	IPI	UniProtKB:Q9UNS2	Human	PMID:15861129
Biological Process	GO:1901796	regulation of signal transduction by p53 class mediator	MLF1	IPI	UniProtKB:Q9UNS2	Human	PMID:15861129

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern