About   Help   FAQ
Mlf1
Gene Detail
Symbol

Name
ID
Mlf1
myeloid leukemia factor 1
MGI:1341819
Synonyms
HLS7
Feature Type
protein coding gene
Genetic Map
Chromosome 3
30.91 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:67374097-67400003 bp, + strand
From VEGA annotation of GRCm38

  25907 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7839  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Mlf1

Human
homologs
Human Homolog MLF1, myeloid leukemia factor 1
NCBI Gene ID 4291
neXtProt AC  NX_P58340
Human Chr (Location)  3q25.1; chr3:158571164-158606460 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Interactions
Mlf1 interacts with 52 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process cell cycle, cell cycle arrest, ...
Component cytoplasm, nucleus
Function DNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (37)    Tissues (9)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 37
cDNA source data(68)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(68) cDNA(68)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000022658 (Evidence)
Ensembl Gene ModelENSMUSG00000048416 (Evidence)
Entrez Gene17349 (Evidence)
UniGene10414
DFCITC1587664, TC1580827
DoTSDT.94291412, DT.94291411, DT.492199
NIA Mouse Gene IndexU003305
Consensus CDS ProjectCCDS17395.1, CCDS17396.1
International Mouse Knockout Project StatusMlf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022658 VEGA Gene Model | MGI Sequence Detail 25907 C57BL/6J ±  kb
transcript OTTMUST00000054285 VEGA | MGI Sequence Detail 1113 Not Applicable 
polypeptide OTTMUSP00000025895 VEGA | MGI Sequence Detail 282 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(4) UniProt(5)
Polymorphisms
RFLP(1) : SNPs within 2kb(116 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR019376 Myeloid leukemia factor
Protein Ontology PR:000010439 myeloid leukemia factor 1
References
(Earliest) J:56033 Hitzler JK, et al., cDNA cloning, expression pattern, and chromosomal localization of Mlf1, murine homologue of a gene involved in myelodysplasia and acute myeloid leukemia. Am J Pathol. 1999 Jul;155(1):53-9
(Latest) J:178379 Richard AF, et al., Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression. Dev Biol. 2011 Nov 15;359(2):303-20
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/18/2014
MGI 5.20
The Jackson Laboratory