Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MICU1
  • Mouse genes Micu1
  • Rat genes Micu1
  • Zfish genes micu1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Micu1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	MICU1	IDA		Human	PMID:23101630
Molecular Function	GO:0005509	calcium ion binding	MICU1	IDA		Human	PMID:24514027
Molecular Function	GO:0005509	calcium ion binding	Micu1	IMP		Mouse	MGI:MGI:5558955|PMID:24560927
Molecular Function	GO:0042802	identical protein binding	MICU1	IPI	UniProtKB:Q9BPX6	Human	PMID:24514027
Molecular Function	GO:0005515	protein binding	MICU1	IPI	UniProtKB:Q8NE86	Human	PMID:21685886
Molecular Function	GO:0005515	protein binding	MICU1	IPI	UniProtKB:Q8NE86-1	Human	PMID:21685886
Molecular Function	GO:0005515	protein binding	MICU1	IPI	UniProtKB:Q8NE86	Human	PMID:23101630
Molecular Function	GO:0005515	protein binding	MICU1	IPI	UniProtKB:Q8NE86	Human	PMID:23178883
Molecular Function	GO:0005515	protein binding	MICU1	IPI	UniProtKB:Q8NE86-1	Human	PMID:23178883
Molecular Function	GO:0005515	protein binding	MICU1	IPI	UniProtKB:Q9BV35	Human	PMID:24430870
Molecular Function	GO:0005515	protein binding	MICU1	IPI	UniProtKB:Q8IYU8	Human	PMID:24560927
Molecular Function	GO:0005515	protein binding	MICU1	IPI	UniProtKB:Q8IYU8	Human	PMID:26387864
Molecular Function	GO:0005515	protein binding	MICU1	IPI	UniProtKB:Q8N4Q1	Human	PMID:26387864
Molecular Function	GO:0005515	protein binding	MICU1	IPI	UniProtKB:Q8NE86	Human	PMID:26387864
Molecular Function	GO:0005515	protein binding	MICU1	IPI	UniProtKB:Q9H4I9	Human	PMID:27099988
Molecular Function	GO:0005515	protein binding	MICU1	IPI	UniProtKB:Q8IYU8	Human	PMID:32494073
Molecular Function	GO:0005515	protein binding	MICU1	IPI	UniProtKB:Q8NE86	Human	PMID:32494073
Molecular Function	GO:0005515	protein binding	Micu1	IPI	UniProtKB:Q8CD10	Mouse	MGI:MGI:5558955|PMID:24560927
Molecular Function	GO:0046982	protein heterodimerization activity	MICU1	IPI	UniProtKB:Q8IYU8	Human	PMID:24560927
Molecular Function	GO:0046982	protein heterodimerization activity	MICU1	IPI	UniProtKB:Q8IYU8	Human	PMID:26387864
Molecular Function	GO:0046982	protein heterodimerization activity	Micu1	IPI	UniProtKB:Q8CD10	Mouse	MGI:MGI:5558955|PMID:24560927
Cellular Component	GO:0034704	calcium channel complex	Micu1	IDA		Mouse	MGI:MGI:5487704|PMID:23409044
Cellular Component	GO:0005743	mitochondrial inner membrane	MICU1	IDA		Human	PMID:20693986
Cellular Component	GO:0005743	mitochondrial inner membrane	MICU1	IMP		Human	PMID:27099988
Cellular Component	GO:0005758	mitochondrial intermembrane space	MICU1	IDA		Human	PMID:24231807
Cellular Component	GO:0005758	mitochondrial intermembrane space	MICU1	IDA		Human	PMID:24560927
Cellular Component	GO:0031966	mitochondrial membrane	MICU1	IDA		Human	PMID:23101630
Cellular Component	GO:0005739	mitochondrion	MICU1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Micu1	HDA		Mouse	PMID:18614015
Cellular Component	GO:1990246	uniplex complex	MICU1	IPI		Human	PMID:32494073
Cellular Component	GO:1990246	uniplex complex	MICU1	IDA		Human	PMID:24231807
Cellular Component	GO:1990246	uniplex complex	MICU1	IDA		Human	PMID:24560927
Biological Process	GO:0036444	calcium import into the mitochondrion	MICU1	IMP		Human	PMID:26903221
Biological Process	GO:0036444	calcium import into the mitochondrion	MICU1	IDA		Human	PMID:32494073
Biological Process	GO:0070509	calcium ion import	MICU1	IDA		Human	PMID:20693986
Biological Process	GO:0051560	mitochondrial calcium ion homeostasis	MICU1	IMP		Human	PMID:20693986
Biological Process	GO:0051560	mitochondrial calcium ion homeostasis	MICU1	IMP		Human	PMID:23101630
Biological Process	GO:0051560	mitochondrial calcium ion homeostasis	MICU1	IMP		Human	PMID:26903221
Biological Process	GO:0051560	mitochondrial calcium ion homeostasis	MICU1	IMP		Human	PMID:27099988
Biological Process	GO:0051560	mitochondrial calcium ion homeostasis	MICU1	IDA		Human	PMID:32494073
Biological Process	GO:0006851	mitochondrial calcium ion transmembrane transport	MICU1	IMP		Human	PMID:23101630
Biological Process	GO:0006851	mitochondrial calcium ion transmembrane transport	MICU1	IDA		Human	PMID:24560927
Biological Process	GO:0006851	mitochondrial calcium ion transmembrane transport	MICU1	IMP		Human	PMID:27099988
Biological Process	GO:0051561	positive regulation of mitochondrial calcium ion concentration	MICU1	IDA		Human	PMID:24560927
Biological Process	GO:0051561	positive regulation of mitochondrial calcium ion concentration	MICU1	IMP		Human	PMID:26975899
Biological Process	GO:0051260	protein homooligomerization	MICU1	IDA		Human	PMID:24514027
Biological Process	GO:1900069	regulation of cellular hyperosmotic salinity response	MICU1	IMP		Human	PMID:26975899

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern