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Micu1 Gene Detail
Summary
  • Symbol
    Micu1
  • Name
    mitochondrial calcium uptake 1
  • Synonyms
    C730016L05Rik, Cbara1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384909
    NCBI Gene: 216001
  • Gene Overview
    MyGene.info: MICU1
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:59702482-59864134 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 29.60 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1211 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384909
protein coding gene Chr10:59702477-59864134 (.)
129S1/SvImJ MGP_129S1SvImJ_G0017260
protein coding gene Chr10:58884968-59044933 (+)
A/J MGP_AJ_G0017237
protein coding gene Chr10:57159056-57319622 (+)
AKR/J MGP_AKRJ_G0017196
protein coding gene Chr10:58629299-58788387 (+)
BALB/cJ MGP_BALBcJ_G0017198
protein coding gene Chr10:57227487-57405598 (+)
C3H/HeJ MGP_C3HHeJ_G0017021
protein coding gene Chr10:58562099-58726592 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017656
protein coding gene Chr10:60983943-61157633 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015347
protein coding gene Chr10:54193893-54345834 (+)
CAST/EiJ MGP_CASTEiJ_G0016592
protein coding gene Chr10:58500799-58656316 (+)
CBA/J MGP_CBAJ_G0016993
protein coding gene Chr10:63176858-63344918 (+)
DBA/2J MGP_DBA2J_G0017098
protein coding gene Chr10:56473489-56628995 (+)
FVB/NJ MGP_FVBNJ_G0017092
protein coding gene Chr10:55708423-55866151 (+)
LP/J MGP_LPJ_G0017173
protein coding gene Chr10:59253683-59425249 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017120
protein coding gene Chr10:65684458-65849621 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017693
protein coding gene Chr10:58443050-58612291 (+)
PWK/PhJ MGP_PWKPhJ_G0016375
protein coding gene Chr10:56280648-56438897 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016158
protein coding gene Chr10:57793986-57955897 (+)
WSB/EiJ MGP_WSBEiJ_G0016656
protein coding gene Chr10:58366665-58524987 (+)



Homology
more
  • Human Ortholog
    MICU1, mitochondrial calcium uptake 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MICU1, mitochondrial calcium uptake 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ara CALC, CALC, CBARA1, EFHA3, MPXPS
  • Links
    NCBI Gene ID: 10367
    neXtProt AC: NX_Q9BPX6
    UniProt: Q9BPX6

  • Chr Location
    10q22.1; chr10:72367326-72626191 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 4431
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MICU1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 216001 NCBI Gene Model | MGI Sequence Detail 161653 C57BL/6J ±  kb
transcript NM_001291442 RefSeq | MGI Sequence Detail 2376 C57BL/6  
polypeptide Q8VCX5 UniProt | EBI | MGI Sequence Detail 477 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 108
    cDNA 108

    Microarray probesets 3
Other
Accession IDs
less
MGI:2443095
References
more
  • Summaries
    All 45
    Gene Ontology 6
    Phenotypes 14
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:250763 Paillard M, et al., Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca(2+) Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU. Cell Rep. 2017 Mar 7;18(10):2291-2300

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory