Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MFSD8
  • Mouse genes Mfsd8
  • Rat genes Mfsd8
  • Zfish genes mfsd8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mfsd8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0005765	lysosomal membrane	MFSD8	HDA		Human	PMID:17897319
Cellular Component	GO:0005764	lysosome	Mfsd8	IDA		Mouse	PMID:24423645
Cellular Component	GO:0005764	lysosome	Mfsd8	IDA		Mouse	PMID:20826447
Cellular Component	GO:0016020	membrane	Mfsd8	IDA		Mouse	PMID:26681805
Biological Process	GO:0097352	autophagosome maturation	Mfsd8	IMP		Mouse	PMID:29514215
Biological Process	GO:0007040	lysosome organization	Mfsd8	IMP		Mouse	PMID:24423645
Biological Process	GO:0007040	lysosome organization	Mfsd8	IMP	MGI:MGI:4456699	Mouse	PMID:26681805
Biological Process	GO:0048666	neuron development	Mfsd8	IMP	MGI:MGI:4456699	Mouse	PMID:26681805
Biological Process	GO:0010506	regulation of autophagy	Mfsd8	IMP	MGI:MGI:4456699	Mouse	PMID:26681805
Biological Process	GO:1905165	regulation of lysosomal protein catabolic process	Mfsd8	IMP		Mouse	PMID:29514215
Biological Process	GO:0038202	TORC1 signaling	Mfsd8	IMP		Mouse	PMID:29514215

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern