Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes METTL5
  • Mouse genes Mettl5
  • Rat genes Mettl5
  • Zfish genes mettl5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mettl5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	METTL5	IPI	UniProtKB:Q9UI30	Human	PMID:31328227
Molecular Function	GO:0005515	protein binding	METTL5	IPI	UniProtKB:O15062	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	METTL5	IPI	UniProtKB:Q9UI30	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	METTL5	IPI	UniProtKB:Q9UI30	Human	PMID:34948388
Molecular Function	GO:0005515	protein binding	METTL5	IPI	UniProtKB:Q9UI30	Human	PMID:35033535
Molecular Function	GO:0008988	rRNA (adenine-N6-)-methyltransferase activity	METTL5	IDA		Human	PMID:31328227
Molecular Function	GO:0008988	rRNA (adenine-N6-)-methyltransferase activity	METTL5	IDA		Human	PMID:32217665
Molecular Function	GO:0008988	rRNA (adenine-N6-)-methyltransferase activity	METTL5	IDA		Human	PMID:33357433
Molecular Function	GO:0008988	rRNA (adenine-N6-)-methyltransferase activity	METTL5	IDA		Human	PMID:33428944
Molecular Function	GO:0008988	rRNA (adenine-N6-)-methyltransferase activity	METTL5	IDA		Human	PMID:35033535
Molecular Function	GO:0008988	rRNA (adenine-N6-)-methyltransferase activity	Mettl5	IDA		Mouse	MGI:MGI:6505165|PMID:32783360
Molecular Function	GO:1904047	S-adenosyl-L-methionine binding	METTL5	IDA		Human	PMID:31328227
Cellular Component	GO:0005829	cytosol	METTL5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001650	fibrillar center	METTL5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	METTL5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	METTL5	IDA		Human	PMID:31564433
Cellular Component	GO:0098794	postsynapse	METTL5	IDA		Human	PMID:31564433
Cellular Component	GO:0098793	presynapse	METTL5	IDA		Human	PMID:31564433
Biological Process	GO:0045727	positive regulation of translation	METTL5	IMP		Human	PMID:33357433
Biological Process	GO:0045727	positive regulation of translation	Mettl5	IMP		Mouse	MGI:MGI:6436417|PMID:32217665
Biological Process	GO:0045727	positive regulation of translation	Mettl5	IMP		Mouse	MGI:MGI:6505165|PMID:32783360
Biological Process	GO:0031167	rRNA methylation	METTL5	IDA		Human	PMID:31328227
Biological Process	GO:0031167	rRNA methylation	METTL5	IDA		Human	PMID:32217665
Biological Process	GO:0031167	rRNA methylation	METTL5	IDA		Human	PMID:33357433
Biological Process	GO:0031167	rRNA methylation	METTL5	IDA		Human	PMID:33428944
Biological Process	GO:0031167	rRNA methylation	METTL5	IDA		Human	PMID:35033535
Biological Process	GO:0031167	rRNA methylation	Mettl5	IDA		Mouse	MGI:MGI:6884948|PMID:35033535
Biological Process	GO:0031167	rRNA methylation	Mettl5	IDA		Mouse	MGI:MGI:6505165|PMID:32783360
Biological Process	GO:0048863	stem cell differentiation	Mettl5	IMP		Mouse	MGI:MGI:6436417|PMID:32217665
Biological Process	GO:0048863	stem cell differentiation	Mettl5	IMP		Mouse	MGI:MGI:6505165|PMID:32783360

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern