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Mettl5 Gene Detail
Summary
  • Symbol
    Mettl5
  • Name
    methyltransferase like 5
  • Synonyms
    2810410A08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922672
    NCBI Gene: 75422
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:69871198-69885615 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 40.95 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    76 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922672
protein coding gene Chr2:69871195-69885910 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025808
protein coding gene Chr2:69867902-69887793 (-)
A/J MGP_AJ_G0025785
protein coding gene Chr2:67174667-67189603 (-)
AKR/J MGP_AKRJ_G0025754
protein coding gene Chr2:68992967-69009385 (-)
BALB/cJ MGP_BALBcJ_G0025780
protein coding gene Chr2:67335767-67350220 (-)
C3H/HeJ MGP_C3HHeJ_G0025540
protein coding gene Chr2:69227168-69241770 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026227
protein coding gene Chr2:71982736-71998445 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023630
protein coding gene Chr2:64400270-64415356 (-)
CAST/EiJ MGP_CASTEiJ_G0025004
protein coding gene Chr2:69340084-69355891 (-)
CBA/J MGP_CBAJ_G0025520
protein coding gene Chr2:74640310-74654062 (-)
DBA/2J MGP_DBA2J_G0025651
protein coding gene Chr2:66808161-66822140 (-)
FVB/NJ MGP_FVBNJ_G0025614
protein coding gene Chr2:66188292-66204117 (-)
LP/J MGP_LPJ_G0025740
protein coding gene Chr2:69729775-69746776 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025643
protein coding gene Chr2:76700329-76717429 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026284
protein coding gene Chr2:69078018-69093298 (-)
PWK/PhJ MGP_PWKPhJ_G0024745
protein coding gene Chr2:66659107-66673463 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024552
protein coding gene Chr2:69309706-69327520 (-)
WSB/EiJ MGP_WSBEiJ_G0025072
protein coding gene Chr2:69508920-69524353 (-)



Homology
more
  • Human Ortholog
    METTL5, methyltransferase like 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    METTL5, methyltransferase like 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HSPC133
  • Links
    NCBI Gene ID: 29081
    neXtProt AC: NX_Q9NRN9
    UniProt: Q9NRN9

  • Chr Location
    2q31.1; chr2:169811757-169824931 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    35
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    33
  • Genomic Mutations
    1 involving Mettl5
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051730 Ensembl Gene Model | MGI Sequence Detail 14418 C57BL/6J ±  kb
transcript ENSMUST00000060447 Ensembl | MGI Sequence Detail 968 Not Applicable  
polypeptide ENSMUSP00000050907 Ensembl | MGI Sequence Detail 209 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory