Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MED21
  • Mouse genes Med21
  • Rat genes Med21
  • Zfish genes med21
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Med21

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q9NWA0	Human	PMID:14638676
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q9NWA0	Human	PMID:15175163
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:P63208-1	Human	PMID:22479149
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:O43513	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q15648	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q9NPJ6	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q9NWA0	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:O43513	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q15648	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q9NPJ6	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q9NWA0	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q9NPJ6	Human	PMID:25281560
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:A1L4H1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:O15481	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q8N720	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q9UL45	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:O43513	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q15648	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q9NPJ6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q9NWA0	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:A1L4H1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:O14964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:O15481	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q6ZMU5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q96GS4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q9NQG6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q13449	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MED21	IPI	UniProtKB:Q9BVL2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Med21	IPI	PR:Q9D828	Mouse	PMID:11591653
Molecular Function	GO:0003713	transcription coactivator activity	MED21	IDA		Human	PMID:12037571
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Med21	IDA		Rat	PMID:12149480|RGD:2304264
Cellular Component	GO:0070847	core mediator complex	MED21	IPI		Human	PMID:24882805
Cellular Component	GO:0016592	mediator complex	MED21	IDA		Human	PMID:12037571
Cellular Component	GO:0016592	mediator complex	Med21	IDA		Mouse	PMID:15340084
Cellular Component	GO:0016592	mediator complex	Med21	IDA		Mouse	PMID:12093747
Cellular Component	GO:0005634	nucleus	MED21	IDA		Human	PMID:24882805
Cellular Component	GO:0000151	ubiquitin ligase complex	Med21	IDA		Rat	PMID:12149480|RGD:2304264
Biological Process	GO:0001824	blastocyst development	Med21	IMP	MGI:MGI:2445456	Mouse	PMID:10500093
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MED21	IDA		Human	PMID:12037571
Biological Process	GO:0016567	protein ubiquitination	Med21	IDA		Rat	PMID:12149480|RGD:2304264
Biological Process	GO:0035019	somatic stem cell population maintenance	Med21	IMP		Mouse	PMID:20720539

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern