Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MCM6
  • Mouse genes Mcm6
  • Rat genes Mcm6
  • Zfish genes mcm6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mcm6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003678	DNA helicase activity	MCM6	IDA		Human	PMID:25661590
Molecular Function	GO:0003678	DNA helicase activity	MCM6	IDA		Human	PMID:9305914
Molecular Function	GO:0003678	DNA helicase activity	Mcm6	IDA		Mouse	MGI:MGI:2429455|PMID:12207017
Molecular Function	GO:0003678	DNA helicase activity	Mcm6	IMP		Mouse	MGI:MGI:1353541|PMID:10567526
Molecular Function	GO:0003678	DNA helicase activity	Mcm6	IDA		Mouse	PMID:15917436
Molecular Function	GO:0042802	identical protein binding	MCM6	IPI	UniProtKB:Q14566	Human	PMID:15232106
Molecular Function	GO:0042802	identical protein binding	MCM6	IPI	UniProtKB:Q14566	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q7L590	Human	PMID:11095689
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P25205	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q7L590	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P49736	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q7L590	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P33993	Human	PMID:16438930
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q14683	Human	PMID:16438930
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P49736	Human	PMID:16899510
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q08945	Human	PMID:16902406
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P25205	Human	PMID:17296731
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P33993	Human	PMID:17296731
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P49736	Human	PMID:17296731
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q9BTE3	Human	PMID:17296731
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P42771	Human	PMID:17955473
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q9H211	Human	PMID:20202939
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P49736	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q05086	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q76353	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P49736	Human	PMID:22540012
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q9BTE3	Human	PMID:22540012
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P33993	Human	PMID:23764002
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q9BTE3	Human	PMID:24299456
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q9BTE3	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P08579	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P49736	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P50583	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q3B820	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q7L590-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q96C00	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P49736	Human	PMID:26167883
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P25205	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P33993	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P49736	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q9H211	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:P25205	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q08945	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q7L590-2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q5TDH0	Human	PMID:29290612
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q05086	Human	PMID:29426014
Molecular Function	GO:0005515	protein binding	MCM6	IPI	UniProtKB:Q05086-2	Human	PMID:29426014
Molecular Function	GO:0005515	protein binding	Mcm6	IPI	UniProtKB:Q8R4E9	Mouse	MGI:MGI:2388867|PMID:12192004
Molecular Function	GO:0005515	protein binding	Mcm6	IPI	UniProtKB:Q8R4E9	Mouse	MGI:MGI:6810788|PMID:15811859
Molecular Function	GO:0005515	protein binding	Mcm6	IPI	PR:P49717	Mouse	PMID:15917436
Molecular Function	GO:0005515	protein binding	Mcm6	IPI	PR:Q61881	Mouse	PMID:15917436
Molecular Function	GO:0003697	single-stranded DNA binding	MCM6	IDA		Human	PMID:25661590
Molecular Function	GO:0003697	single-stranded DNA binding	Mcm6	IDA		Mouse	MGI:MGI:2429455|PMID:12207017
Molecular Function	GO:0003697	single-stranded DNA binding	Mcm6	IMP		Mouse	MGI:MGI:1353541|PMID:10567526
Molecular Function	GO:0003697	single-stranded DNA binding	Mcm6	IPI	PR:Q61881	Mouse	PMID:15917436
Molecular Function	GO:0003697	single-stranded DNA binding	Mcm6	IPI	PR:P49717	Mouse	PMID:15917436
Cellular Component	GO:0000781	chromosome, telomeric region	MCM6	HDA		Human	PMID:19135898
Cellular Component	GO:0071162	CMG complex	MCM6	IPI		Human	PMID:22474384
Cellular Component	GO:0042555	MCM complex	MCM6	IPI		Human	PMID:22540012
Cellular Component	GO:0042555	MCM complex	MCM6	IDA		Human	PMID:17296731
Cellular Component	GO:0042555	MCM complex	MCM6	IDA		Human	PMID:25661590
Cellular Component	GO:0042555	MCM complex	Mcm6	IDA		Mouse	MGI:MGI:1353541|PMID:10567526
Cellular Component	GO:0042555	MCM complex	Mcm6	IDA		Mouse	MGI:MGI:2429455|PMID:12207017
Cellular Component	GO:0005654	nucleoplasm	MCM6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MCM6	IDA		Human	PMID:16899510
Cellular Component	GO:0005634	nucleus	MCM6	IDA		Human	PMID:22474384
Cellular Component	GO:0005634	nucleus	Mcm6	IDA		Mouse	PMID:11555636
Biological Process	GO:0006268	DNA unwinding involved in DNA replication	MCM6	IDA		Human	PMID:22474384
Biological Process	GO:0006268	DNA unwinding involved in DNA replication	Mcm6	IPI	PR:Q61881	Mouse	PMID:15917436
Biological Process	GO:0006268	DNA unwinding involved in DNA replication	Mcm6	IPI	PR:P49717	Mouse	PMID:15917436

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern