Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MCM10
  • Mouse genes Mcm10
  • Rat genes Mcm10
  • Zfish genes mcm10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mcm10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	Mcm10	IPI	UniProtKB:Q0VGM9	Mouse	MGI:MGI:5522574|PMID:24115439
Molecular Function	GO:0042802	identical protein binding	MCM10	IPI	UniProtKB:Q7L590	Human	PMID:17823614
Molecular Function	GO:0005515	protein binding	MCM10	IPI	UniProtKB:P49736	Human	PMID:11095689
Molecular Function	GO:0005515	protein binding	MCM10	IPI	UniProtKB:Q13416	Human	PMID:11095689
Molecular Function	GO:0005515	protein binding	MCM10	IPI	UniProtKB:Q14566	Human	PMID:11095689
Molecular Function	GO:0005515	protein binding	MCM10	IPI	UniProtKB:Q13416	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	MCM10	IPI	UniProtKB:Q14566	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	MCM10	IPI	UniProtKB:Q14566	Human	PMID:16189514
Cellular Component	GO:0005730	nucleolus	MCM10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MCM10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MCM10	IDA		Human	PMID:11095689
Cellular Component	GO:0005634	nucleus	MCM10	IMP		Human	PMID:32865517
Biological Process	GO:0008283	cell population proliferation	Mcm10	IMP	MGI:MGI:5296322	Mouse	PMID:21693137
Biological Process	GO:0006974	DNA damage response	MCM10	IMP		Human	PMID:24726359
Biological Process	GO:0006270	DNA replication initiation	MCM10	IMP		Human	PMID:32865517

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern